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p53-Independent checkpoint controls in a plant cell model
(Sociedad de Biología de Chile, 2003)
The G2 checkpoint activated by DNA damage does not prevent genome instability in plant cells
(Sociedad de Biología de Chile, 2006)
Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals
(Society of Biology of Chile, 2012)
We analyzed the in vitro effects of the anti-tumoral drugs doxorubicin, cytosine arabinoside and hydroxyurea on the G2-prophase checkpoint in lymphocytes from healthy individuals. At biologically equivalent concentrations, ...
G2 checkpoint-dependent DNA repair and its response to catalase in Down syndrome and control lymphocyte cultures
(2007)
The amount of DNA lesions repaired in G2 and also G2 timing are controlled by the DNA damage-dependent checkpoint. Down syndrome (DS) lymphocytes showed twice as much constitutive DNA damage in G2 than control ones, when ...
Arquitetura de configuração dinâmica para a técnica de checkpoint em frameworks de processamento distribuído
(Universidade Federal de Santa MariaBrasilCiência da ComputaçãoUFSMPrograma de Pós-Graduação em Ciência da ComputaçãoCentro de Tecnologia, 2019-08-05)
Processing data on High-Performance Computing (HPC) systems is a communal assignment
due to large amounts of information being generated. However, reliability and performance
problems are created as these systems complexity ...
Roles of nibrin and ATM/ATR kinases on the G2 checkpoint under endogenous or radio-induced DNA damage
(Sociedad de Biología de Chile, 2005)
The G2 checkpoint activated by DNA damage does not prevent genome instability in plant cells
(2006)
Root growth, G2 length, and the frequency of aberrant mitoses and apoptotic nuclei were recorded after a
single X-ray irradiation, ranging from 2.5 to 40 Gy, in Allium cepa L. root meristematic cells. After 72 h of
recovery, ...
Targeted therapy to annihilate the immune-evading phenotype in cancer evolution
(Informa Healthcare, 2018-07)
Cancer is a moving target, and targeted therapy must ultimatelydeal with the evolution of the disease. This is becauseevolution is the substrate for development of resistance totargeted therapy. A successful therapeutic ...
Gastric cancer in the era of immune checkpoint blockade
(2019-09-24)
Gastric cancer (GC) is one of the most important malignancies worldwide because of its high incidence and mortality. The very low survival rates are mainly related to late diagnosis and limited treatment options. GC is the ...