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p53-Independent checkpoint controls in a plant cell model
(Sociedad de Biología de Chile, 2003)
Making Targeted Therapy Compatible with Checkpoint Immunotherapy
(Elsevier Science London, 2017-07)
Immune checkpoint blockades induced by antibodies are revolutionizing cancer therapy. Combinations of checkpoint immunotherapies with kinase inhibitors (KIs) are being clinically evaluated as oncogenic mutations arise. ...
The G2 checkpoint activated by DNA damage does not prevent genome instability in plant cells
(Sociedad de Biología de Chile, 2006)
Mapeamento sistemático de ferramentas que auxiliam na instrumentação de checkpoints em aplicações de computação de alto desempenhoSystematic mapping of tools that assist checkpoint instrumentation in high performance computing application
(Universidade Federal da Grande DouradosBrasilFaculdade de Ciências Exatas e TecnologiaUFGD, 2019)
The Epstein-Barr Virus Hacks Immune Checkpoints: Evidence and Consequences for Lymphoproliferative Disorders and Cancers
(2022-03-01)
The Epstein-Barr Virus (EBV) is a gammaherpesvirus involved in the etiopathogenesis of a variety of human cancers, mostly of lymphoid and epithelial origin. The EBV infection participates in both cell transformation and ...
G2 checkpoint-dependent DNA repair and its response to catalase in Down syndrome and control lymphocyte cultures
(2007)
The amount of DNA lesions repaired in G2 and also G2 timing are controlled by the DNA damage-dependent checkpoint. Down syndrome (DS) lymphocytes showed twice as much constitutive DNA damage in G2 than control ones, when ...
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
(Sociedad de Biología de Chile, 2002)
Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals
(Society of Biology of Chile, 2012)
We analyzed the in vitro effects of the anti-tumoral drugs doxorubicin, cytosine arabinoside and hydroxyurea on the G2-prophase checkpoint in lymphocytes from healthy individuals. At biologically equivalent concentrations, ...