Buscar
Mostrando ítems 1-10 de 392
Fatty acid regulation of voltage- and ligand-gated ion channel function
(Frontiers Research Foundation, 2016-11-28)
Free fatty acids (FFA) are essential components of the cell, where they play a key role in lipid and carbohydrate metabolism, and most particularly in cell membranes, where they are central actors in shaping the physicochemical ...
Marine Toxins Targeting Ion Channels
(Molecular Diversity Preservation International, 2006-04)
This introductory minireview points out the importance of ion channels for cell communication. The basic concepts on the structure and function of ion channels triggered by membrane voltage changes, the so-called voltage-gated ...
Phylogenetic conservation of protein-lipid motifs in pentameric ligand-gated ion channels
(Elsevier Science, 2015-07)
Using the crosstalk between the nicotinic acetylcholine receptor (nAChR) and its lipid microenvironment as a paradigm, this short overview analyzes the occurrence of structural motifs which appear not only to be conserved ...
Radiative decay channel assessment to understand the sensing mechanism of a fluorescent turn-on Al3+ chemosensor
(John Wiley and Sons Inc., 2020)
A change in the ion selectivity of ligand-gated ion channels provides a mechanism to switch behavior.
(Public Library Of Science, 2015-09)
Behavioral output of neural networks depends on a delicate balance between excitatory and inhibitory synaptic connections. However, it is not known whether network formation and stability is constrained by the sign of ...
Orthosteric and Allosteric Activation of Human 5-HT3A Receptors
(Cell Press, 2020-10-20)
The serotonin type 3 receptor (5-HT 3) is a ligand-gated ion channel that converts the binding of the neurotransmitter serotonin (5-HT) into a transient cation current that mediates fast excitatory responses in peripheral ...
A structural view of ligand-dependent activation in thermoTRP channels
(Frontiers Research Foundation, 2014)
Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped into seven sub-families. Although great advances have been made regarding the activation and modulation of TRP channel activity, ...
The interaction of ryanoids with individual ryanodine receptor channels
(Sociedad de Biología de Chile, 2004)
A structural view of ligand-dependent activation in thermotrp channels
(FRONTIERS RESEARCH FOUNDATION, 2014)