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Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
(BMC, 2020)
Background: In type I diabetes mellitus (T1DM) pancreatic beta cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet ...
Microencapsulation of cellular aggregates composed of diferentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
(2020)
Background: In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transplant ...
Scanning and transmission electron microscopy of transformed Vero cells, with altered in vitro growth characteristics
(Editrice Compositori BolognaBolognaItália, 1996)
Prion protein ablation increases cellular aggregation and embolization contributing to mechanisms of metastasis
(WILEY-LISS, 2009)
Cellular Prion Protein (PrP(C)) is a cell surface protein highly expressed in the nervous system, and to a lesser extent in other tissues. PrP(C) binds to the extracellular matrix laminin and vitronectin, to mediate cell ...
Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation
(Frontiers Media, 2020)
TAR DNA binding protein 43 kDa (TDP-43) is a ribonuclear protein regulating many aspects of RNA metabolism. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD) are fatal neurodegenerative ...
Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation
(2020)
TAR DNA binding protein 43 kDa (TDP-43) is a ribonuclear protein regulating many aspects of RNA metabolism. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD) are fatal neurodegenerative ...
The chaperonin CCT promotes the formation of fibrillar aggregates of gamma-tubulin
(Elsevier, 2018)
The type II chaperonin CCT is involved in the prevention of the pathogenesis of numerous human misfolding disorders, as it sequesters misfolded proteins, blocks their aggregation and helps them to achieve their native ...
Polymer induced condensation of DNA supercoils
(American Institute of Physics (AIP), 2008-11-14)
Macromolecular crowding is thought to be a significant factor driving DNA condensation in prokaryotic cells. Whereas DNA in prokaryotes is supercoiled, studies on crowding-induced DNA condensation have so far focused on ...
A phenolic-rich extract from ugni molinae berries reduces abnormal protein aggregation in a cellular model of huntington's disease
(Public Library Science, 2021)
Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...
Um algoritmo de alto desempenho para evoluir o modelo de Potts Celular
(Universidade do Vale do Rio do Sinos, 2006-01-10)
The simulation of cellular systems has received great interest in the last years. In particular, the cellular Potts model is widely used in the area given its precision in representing these systems. This model, in its ...