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Viral cell-to-cell spread: Conventional and non-conventional ways
(Academic Press Inc., 2020-09-29)
A critical step in the life cycle of a virus is spread to a new target cell, which generally involves the release of new viral particles from the infected cell which can then initiate infection in the next target cell. ...
Image-based Quantification of Direct Cell-to-cell Transmission of Bovine Viral Diarrhea Virus
(Bio-protocol, 2019-08)
Different viruses rely on direct cell-to-cell transmission to propagate infection within the infected host. Measuring this mode of transmission in cultured cells is often complicated by the contribution of cell free viruses ...
Cell-to-cell transmission is the main mechanism supporting bovine viral diarrhea virus spread in cell culture
(American Society for Microbiology, 2019-01)
After initiation of an infective cycle, spread of virus infection can occur fundamentally in two different ways: (i) viral particles can be released into the external environment and diffuse through the extracellular space ...
A new model to study cell-to-cell transfer of αSynuclein in vivo
(Elsevier B.V., 2018)
© 2018 Elsevier Inc. Parkinson's disease (PD) compromises motor control due to the loss of dopaminergic neurons in the substantia nigra pars compacta. At the histopathological level, PD is characterized by the accumulation ...
The metalloprotease Mpl supports Listeria monocytogenes dissemination through resolution of membrane protrusions into vacuoles
(American Society for Microbiology, 2016-06)
Listeria monocytogenes is an intracellular pathogen that disseminates within the intestinal epithelium through acquisition of actin-based motility and formation of plasma membrane protrusions that project into adjacent ...
Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans
(ROYAL SOC, 2008)
The perforated whole-cell configuration of the patch-clamp technique was applied to functionally identified beta-cells in intact mouse pancreatic islets to study the extent of cell coupling between adjacent beta-cells. ...
HIV Controllers Exhibit Effective CD8 + T Cell Recognition of HIV-1-Infected Non-activated CD4 + T Cells
Even with sustained antiretroviral therapy, resting CD4 + T cells remain a persistent reservoir of HIV infection, representing a critical barrier to curing HIV. Here, we demonstrate that CD8 + T cells recognize infected, ...
Contribution of cell proliferation to axial elongation in the red flour beetle Tribolium castaneumlee
(2017)
Most arthropods generate their posterior bodies by adding segments periodically, as the embryo grows, from a posteriorly located region called the segment addition zone. This mode of segmentation is shared with vertebrates ...
Enteroinvasive Escherichia coli vs. Shigella flexneri : how different patterns of gene expression affect virulence
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Important features of the enteroinvasive Escherichia coli (EIEC) phenotype and gene expression likely to confer EIEC with a lower ability to cause disease than Shigella flexneri were described here for the first time. To ...