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AMPK-dependent nitric oxide release provides contractile support during hyperosmotic stress
(Dr Dietrich Steinkopff Verlag, 2018-01)
In different pathological situations, cardiac cells undergo hyperosmotic stress (HS) and cell shrinkage. This change in cellular volume has been associated with contractile dysfunction and cell death. Given that nitric ...
Flavonoid galangin prevents smooth muscle fatigue of pig urinary bladder
(Royal Pharmaceutical Soc Great BritainLondonInglaterra, 2005)
Intestine of dystrophic mice presents enhanced contractile resistance to stretching despite morphological impairment
(Amer Physiological Soc, 2014-02-01)
Protein dystrophin is a component of the dystrophin-associated protein complex, which links the contractile machinery to the plasma membrane and to the extra-cellular matrix. Its absence leads to a condition known as ...
An outside-in switch in integrin signaling caused by chemical and mechanical signals in reactive astrocytes
(Frontiers Media, 2021)
Astrocyte reactivity is associated with poor repair capacity after injury to the brain, where chemical and physical changes occur in the damaged zone. Astrocyte surface proteins, such as integrins, are upregulated, and the ...
Rab11 Regulates Trafficking of Trans-sialidase to the Plasma Membrane through the Contractile Vacuole Complex of Trypanosoma cruzi
(Public Library of Science, 2014-06)
Trypanosoma cruzi is the etiologic agent of Chagas disease. Although this is not a free-living organism it has conserved a contractile vacuole complex (CVC) to regulate its osmolarity. This obligate intracellular pathogen ...
Modulation of smooth muscle cell function: Morphological evidence for a contractile to synthetic transition in the rat ventral prostate after castration
(Elsevier B.V., 2005-09-01)
In this study, we evaluated the involvement of rat ventral prostate smooth muscle cells (SMC) in secretory activity and whether this function is modulated after castration. Cell morphology was examined at both light and ...