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Proteomics of dedifferentiation of SK-N-BE2 neuroblastoma cells
(2014)
Neuroblastoma develops through processes which include cellular dedifferentiation. Ability of tumors to form spheroids is one of the manifestations of dedifferentiation and carcinogenic transformation. To study mechanisms ...
A necessidade atual em se continuar a pesquisar com células-tronco embrionárias
(2013-05-01)
Embryonic stem cells are pluripotent and able to generate all cell types of the body, being the most promising cells to the study for regenerative medicine. Following the differentiation path, there are adult stem cells, ...
A necessidade atual em se continuar a pesquisar com células-tronco embrionárias
(2013-05-01)
Embryonic stem cells are pluripotent and able to generate all cell types of the body, being the most promising cells to the study for regenerative medicine. Following the differentiation path, there are adult stem cells, ...
Oxidative stress promotes proliferation and dedifferentiation of retina glial cells in vitro
(Wiley-liss, Div John Wiley & Sons Inc, 2009-03-14)
Oxidative damage is involved in triggering neuronal death in several retinal neurodegenerative diseases. the recent finding of stem cells in the retina suggests that both preventing neuronal death and replacing lost neurons ...
Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation
(PERGAMON-ELSEVIER SCIENCE LTD., 2016)
Glucagon-like peptide-1 (GLP-1) is a neuroendocrine hormone produced by gastrointestinal tract in response to food ingestion. GLP-1 plays a very important role in the glucose homeostasis by stimulating glucose-dependent ...
The administration of multipotent stromal cells at precancerous stage precludes tumor growth and epithelial dedifferentiation of oral squamous cell carcinoma
(2017)
Multipotent stromal cells (MSCs) are envisioned as a powerful therapeutic tool. As they home into tumors, secrete trophic and vasculogenic factors, and suppress immune response their role in carcinogenesis is a matter of ...