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Transgenic mouse model harboring the transcriptional fusion ccl20-luciferase as a novel reporter of pro-inflammatory response
(Public Library Science, 2013-11-12)
The chemokine CCL20, the unique ligand of CCR6 functions as an attractant of immune cells. Expression of CCL20 is induced by Toll-like Receptor (TLR) signaling or proinflammatory cytokine stimulation. However CCL20 is also ...
Down-regulation of NF-κB signaling by Gordonia bronchialis prevents the activation of gut epithelial cells
(Sage Publications Ltd, 2014-08)
The immunomodulatory power of heat-killed Gordonia bronchialis was studied on gut epithelial cells activated with pro-inflammatory stimuli (flagellin, TNF-α or IL-1β). Light emission of luciferase-transfected epithelial ...
Peptides of amaranth were targeted as containing sequences with potential anti-inflammatory properties
(Elsevier, 2016-03)
The immunomodulatory effect of amaranth peptides on epithelial cells activated through the NF-κB signalling pathway was examined. Results showed that extensive protein hydrolysis from amaranth (23 and 30% degree of hydrolysis) ...
Down-regulation of intestinal epithelial innate response by probiotic yeasts isolated from kefir
(Elsevier Science, 2010-06)
Kefir is obtained by milk fermentation with a complex microbial population included in a matrix of polysaccharide and proteins. Several health-promoting activities has been attributed to kefir consumption. The aim of this ...
Expressão de microRNAs circulantes em pacientes com insuficiência hepática crônica agudizada e experimentação molecular para avaliação funcional dos microRNAs
(2018)
A insuficiência hepática crônica agudizada (do inglês: acute-on-chronic liver failure, ACLF) é uma complicação da cirrose e está associada à falência de um ou mais órgãos e alta mortalidade em curto prazo. Apesar da doença ...