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AMPK signaling pathway is rapidly activated by T3 and regulates the cardiomyocyte growth
(North Holland PublishingLimerick, 2013-08-25)
Previous studies have indicated that AMP-activated protein kinase (AMPK) plays a critical role in the control of cardiac hypertrophy mediated by different stimuli such as thyroid hormone (TH). Although the classical effects ...
Disarray of sarcomeric alpha-actinin in cardiomyocytes infected by Trypanosoma cruzi
(Cambridge University Press, 2020)
Resistance to cardiomyocyte hypertrophy in ae3−/− mice, deficient in the AE3 Cl− /HCO3 − exchanger
(Biomed Central, 2014-07)
Background: Cardiac hypertrophy is central to the etiology of heart failure. Understanding the molecular pathways promoting cardiac hypertrophy may identify new targets for therapeutic intervention. Sodium-proton exchanger ...
Cardiomyogenic differentiation of bone marrow mesenchymal cells: role of cardiac extract from neonatal rat cardiomyocytes
(Elsevier, 2010-02)
Bone marrow mesenchymal stromal cells (BM-MSCs) with regenerative potential have been identified in heart. Whether these cells become new cardiac lineage cells by phenomena of transdifferentiation or fusion is also being ...
Toll-like receptor-2 and interleukin-6 mediate cardiomyocyte protection from apoptosis during Trypanosoma cruzi murine infection
(Springer, 2012-05)
Local innate immunity plays a key role in initiating and coordinating homeostatic and defense responses in the heart. We have previously reported that the cardiotropic parasite Trypanosoma cruzi, the etiological agent of ...
Fibrosis and hypertrophy induced by Trypanosoma cruzi in a three-dimensional cardiomyocyte-culture system
(Oxford University Press, 2019)