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An adaptive hybridizable discontinuous galerkin approach for cardiac electrophysiology
(Wiley, 2018-05)
Cardiac electrophysiology simulations are numerically challenging because of the propagation of a steep electrochemical wave front and thus require discretizations with small mesh sizes to obtain accurate results. In this ...
An adaptive hybridizable discontinuous Galerkin approach for cardiac electrophysiology
(Wiley, 2018)
Cardiac electrophysiology simulations are numerically challenging because of the propagation of a steep electrochemical wave front and thus require discretizations with small mesh sizes to obtain accurate results. In this ...
On the Accuracy of Eikonal Approximations in Cardiac Electrophysiology in the Presence of Fibrosis
(Springer, 2023)
Fibrotic tissue is one of the main risk factors for cardiac arrhythmias. It is therefore a key component in computational studies. In this work, we compare the monodomain equation to two eikonal models for cardiac ...
Molecular mechanisms of cardiac electromechanical remodeling during Chagas disease: Role of TNF and TGF-beta
(Elsevier Science London, 2017)
Chagas disease is caused by the trypanosomatid Trypanosoma cruzi, which chronically causes heart problems in up to 30% of infected patients. Chagas disease was initially restricted to Latin America. However, due to migratory ...
How drugs modulate the performance of the human heart
(2022)
Many drugs interact with ion channels in the cells of our heart and trigger heart rhythm disorders with potentially fatal consequences. Computational modeling can provide mechanistic insight into the onset and propagation ...