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Unexpected diastereotopic behaviour in the 1H NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres
(2005)
1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5′-nitro-2′-furyl)-1,4-dihydropyridine derivatives, which were ...
Crystal structure and NMR spectra of 3-carboethoxy-3-triphenylphosphoranylidene-2-oxopropane triphenyl phosphonium bromide chloroform solvate
(SOCIEDAD CHILENA DE QUIMICA, 1998-12)
The crystal structure of C42H37O3P2Br has been determined by single crystal X-ray diffraction. The title compound is monoclinic, space group P2(1)/n (Nr. 14), with unit cell parameters a = 11.220(6), b = 14.345(10), c = ...
Gas-phase synthesis of 3-carboethoxy-quinolin-4-ones. A comprehensive computational mechanistic study to uncover the dark side of the Gould–Jacobs reaction
(Royal Society of Chemistry, 2016-08)
A set of 3-carboethoxy-quinolin-4-ones has been synthesized from diethyl 2-((arylamino)methylene) malonates through a Gould-Jacobs (G-J) cyclization using the flash vacuum pyrolysis (FVP) method. Mechanistic studies including ...
Unexpected diastereotopic behaviour in the H-1 NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres
(SOC BRASILEIRA QUIMICA, 2005-01)
1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5'-nitro-2'-furyl)-1,4-dihydropyridine derivatives, which were ...
Surface enhanced vibrational (IR and Raman) spectroscopy in the design of chemosensors based on ester functionalized p-tert-butylcalix[4]arene hosts
(AMER CHEMICAL SOC, 2005-12-06)
Surface-enhanced IR (SEIR) and Raman scattering (SERS) have been employed to study the adsorption of ester functionalized tert-butyl calix[4]arenes on Ag and Au nanostructured surfaces as well as their complexes with pyrene. ...
Evaluación hepatotóxica y nefrotóxica de compuestos imidazo (1,2-a) piridinas 2-, 3- sustituidas con actividad antiparasitaria
(23/04/2012)
ABSTRACT: Advances in the research and development of new drugs have made it possible the treatment of long-term incurable diseases. The research on new drugs involves the preparation or isolation of new molecules and the ...