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β-catenin expression during the canine epidermal development
(Latin American Society for Developmental Biology, 2019)
β-catenin plays a central role both in the adherent intercellular junctions, as well as in the canonical Wnt signalling pathway. The study of the expression pattern of this protein during the canine epidermal development ...
Expression of the epidermal stem cell marker p63/CK5 in cutaneous papillomas and cutaneous squamous cell carcinomas of dogs
(Elsevier, 2021-03)
Cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs) are usual epidermal tumours in dogs. CPs and CSCCs probably arise from the neoplastic transformation of the keratinocytes within the stem cell ...
Osteopontin expression and its relationship with prognostic biomarkers in canine mammary carcinomasExpessão de osteopontina e sua relação com biomarcadores prognóstico nos carcinomas mamários caninos
(2020-03-01)
Osteopontin is a glycophosphoprotein implicated in different physiologic and pathologic processes and is known to be involved in progression and metastasis of various cancers in humans, but this relation is still little ...
Dysregulated Expression of Phosphorylated Epidermal Growth Factor Receptor and Phosphatase and Tensin Homologue in Canine Cutaneous Papillomas and Squamous Cell Carcinomas
(Elsevier, 2020-01)
The molecular mechanisms contributing to the development of cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs) are still poorly understood, limiting the ability to identify molecular suitable targets ...
Expression of the hippo signalling pathway effector YAP during canine epidermal tumourigenesis
(Elsevier, 2020-06)
Cutaneous papilloma (CP) and cutaneous squamous cell carcinoma (CSCC) are frequent epidermal tumours in dogs. In this regard, the study of the deregulated activity of signalling molecules during the epidermal tumourigenesis ...
Immunohistochemical expression of selected phosphoproteins of the mTOR signalling pathway in canine cutaneous squamous cell carcinoma
(Elsevier, 2019-03)
Cutaneous squamous cell carcinoma (cSCC) represents one of the most common malignant skin tumors in dogs. Research aimed at clarifying how the deregulated activity of signalling pathways contributes to cSCC progression can ...
Aberrant expression of E-cadherin/β-catenin during epidermal tumourigenesis in dogs
(Elsevier, 2020-04)
Clinically relevant epidermal tumours in dogs include cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs). The development of CPs and CSCCs involves dysregulation in expression of E-cadherin/β-catenin; ...