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Computational model for membrane transporters: Potential implications for cancer
(Frontiers Media, 2021-02-22)
To explain the increased transport of nutrients and metabolites and to control the movement of drug molecules through the transporters to the cancer cells, it is important to understand the exact mechanism of their structure ...
Glucose transporters: expression, regulation and cancer
(Sociedad de Biología de Chile, 2002)
Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile and metabolic flexibility of cancer cells
(Bentham Science Publishers B.V., 2016)
© 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
Mitochondrial functions and melatonin: a tour of the reproductive cancers
(2019-03-15)
Cancers of the reproductive organs have a strong association with mitochondrial defects, and a deeper understanding of the role of this organelle in preneoplastic–neoplastic changes is important to determine the appropriate ...
The phytoestrogens daidzein and equol inhibit the drug transporter BCRP/ABCG2 in breast cancer cells: potential chemosensitizing effect
(Dr Dietrich Steinkopff Verlag, 2017-11)
PURPOSE: The soy isoflavone genistein has been described to up-regulate breast cancer resistance protein (BCRP) and, thus, enhance chemoresistance in breast cancer cells. The aim of this work was to assess the effect of ...
The Mitochondrial Complex(I) ty of Cancer
(Frontiers, 2017)
Recent evidence highlights that the cancer cell energy requirements vary greatly from normal cells and that cancer cells exhibit different metabolic phenotypes with variable participation of both glycolysis and oxidative ...