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Prevalence and impact of founder mutations in hereditary breast cancer in Latin America
(Sociedade Brasileira de Genética, 2015)
Germline variants in DNA repair genes are associated with young-onset head and neck cancer
(2021-11-01)
The genetic predisposition to head and neck carcinomas (HNSCC) and how the known risk factors (papillomavirus infection, alcohol, and tobacco consumption) contribute to the early-onset disease are barely explored. Although ...
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(Wiley-Blackwell, 1997-01-01)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However. ...
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(Wiley-Blackwell, 1997-01-01)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However. ...
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(1997-10-25)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However, ...
Viral agents and their correlation with the genetic profile of predisposition to human neoplastic and autoimmune diseases
(Soc Iberoamericana Informacion Cientifica-s I I CBuenos AiresArgentina, 2009)
Identification of predisposition genes involved in thyroid and breast carcinomas in patients with family history of these tumors by whole exome sequencing
(Amer Assoc Cancer Research, 2015-08-01)
Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes
(2016-04-15)
In colorectal carcinoma (CRC), 35% of cases are known to have a hereditary component, while a lower proportion (∼5%) can be explained by known genetic factors. In this study, copy number variations (CNVs) were evaluated ...