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A novel pH-responsive hydrogel-based on calcium alginate engineered by the previous formation of polyelectrolyte complexes (PECs) intended to vaginal administration
(2017-10-03)
This work aimed to develop a calcium alginate hydrogel as a pH responsive delivery system for polymyxin B (PMX) sustained-release through the vaginal route. Two samples of sodium alginate from different suppliers were ...
Effect of starch filler on calcium-alginate hydrogels loaded with yerba mate antioxidants
(Elsevier, 2013-03)
A liquid extract of yerba mate (Ilex paraguariensis), with antioxidant properties was encapsulated in calcium-alginate hydrogels containing corn starch as filler at different concentrations. Hydrogel beads were characterized ...
Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy
(2017-10-01)
Anti-vascular endothelial growth factor (anti-VEGF) therapy applied to solid tumors is a promising strategy, yet, the challenge to deliver these agents at high drug concentrations together with the maintenance of therapeutic ...
Ca(II) and Ce(III) homogeneous alginate hydrogels from parent alginic acid precursor: a structural study
(Royal Society of Chemistry, 2016-04)
Alginate hydrogels are suitable for the encapsulation of biomolecules and microorganisms for the building of bioactive materials. Several alternatives to the conventional alginate formulation are being studied for a broad ...
Immobilization of enological pectinase in calcium alginate hydrogels: A potential biocatalyst for winemaking
(Elsevier, 2019-03)
A biocatalyst was obtained by immobilizing an enological commercial pectinase within calcium alginate hydrogels using an entrapment technique, and its catalytic activity was evaluated during different storage conditions. ...
Oxidation of sodium alginate and characterization of the oxidized derivatives
(Elsevier, 2007-02-01)
Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized ...
Polysaccharides As Safer Release Systems For Agrochemicals
(SPRINGER FRANCEPARIS, 2015)
Synthesis and characterization of a β-CD-alginate conjugate
(Elsevier, 2006-12-07)
Selective chemical modification of both β-cyclodextrin (β-CD) and sodium alginate (alg) was performed in order to produce an alginate derivative possessing pendant β-CD cavities along the chain. The latter was then fully ...
Characterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilms
(Elsevier Science, 2015-12)
The aim of the present work is the characterization of smart auto-degradable microspheres composed of calcium alginate/high methoxylated pectin containing an alginate lyase (AL) from Sphingobacterium multivorum and ...
Influence of the extraction–purification conditions on final properties of alginates obtained from brown algae (Macrocystis pyrifera)
(Elsevier Science, 2009-03)
In this work, three methods (ethanol, HCl, and CaCl2 routes) of sodium alginate extraction–purification from brown seaweeds (Macrocystis pyrifera) were used in order to study the influence of process conditions on final ...