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The effect of calcium on non-heme iron uptake, efflux, and transport in intestinal-like epithelial cells (Caco-2 cells)
(2012)
It has been suggested that calcium inhibits the absorption of dietary iron by directly affecting enterocytes. However, it is not clear if this effect is due to a decreased uptake of iron or its efflux from enterocytes. We ...
Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line
(Elsevier, 2009-10)
Background: ATP exerts diverse effects on various cell types via speci fi c purinergic P2Y receptors. Intracellular signaling cascades are the main routes of communication between P2Y receptors and regulatory targets in ...
Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
(Sociedade Brasileira de Microbiologia, 2021)
Intestinal epithelia (Caco-2) cells acquire iron through the basolateral endocytosis of transferrin
(1996)
Although the absorption of iron through the intestinal epithelia is inversely related to body iron stores, the mechanisms by which the enterocytes sense body iron stores are unknown. Polarized enterocytes have transferrin ...
Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress
(Elsevier, 2013-07)
We have previously demonstrated that parathyroid hormone (PTH) induces apoptosis in human colon adenocarcinoma Caco-2 cells but the effects of its tumoral analog PTH-related peptide (PTHrP) in this cell line are still ...
MAP kinases in proliferating human colon cancer Caco-2-cells
(Springer, 2009)
Cyto- and genotoxicity of a vanadyl(IV) complex with oxodiacetate in human colon adenocarcinoma (Caco-2) cells: potential use in cancer therapy
(Springer, 2011-06)
The complex of vanadyl(IV) cation with oxodiacetate, VO(oda) caused an inhibitory effect on the proliferation of the human colon adenocarcinoma cell line Caco-2 in the range of 25–100 lM (P\0.001). This inhibition was ...
Molecular Mechanisms Associated With PTHrP-Induced Proliferation of Colon Cancer Cells
(Wiley, 2014-12)
Parathyroid Hormone-related Protein (PTHrP) is normally produced in many tissues and is recognized for its endocrine, paracrine, autocrine and intracrine modes of action. PTHrP is also implicated in different types of ...