RNA splicing has been recognized in recent years as a pivotal player in heart development and disease. The Ca2C/calmodulin dependent protein kinase II delta (CaMKIId) is a multifunctional Ser/Thr kinase family and generates ...

CaMKII is a major synaptic protein that is activated during the induction of long-term potentiation (LTP) by the Ca2+ influx through NMDARs. This activation is required for LTP induction, but the role of the kinase in the ...

CaMKII is a major synaptic protein that is activated during the induction of long-term potentiation (LTP) by the Ca2+ influx through NMDARs. This activation is required for LTP induction, but the role of the kinase in the ...

Testosterone is known to induce cardiac hypertrophy through androgen receptor (AR)-dependent and -independent pathways, but the molecular underpinnings of the androgen action remain poorly understood. Previous work has ...

Titin-based passive stiffness is post-translationally regulated by several kinases that phosphorylate specific spring elements located within titin's elastic I-band region. Whether titin is phosphorylated by calcium/calmodulin ...

CDK5 is a serine/threonine kinase that is involved in the normal function of the adult brain and plays a role in neurotransmission and synaptic plasticity. However, its over-regulation has been associated with Tau ...

Classic psychedelics are substances known for altering consciousness. Its psychoactive effect is dependent on 5-HT2A and 5-HT1A serotonergic receptors, but due to the long prohibition of these drugs, little is known about ...