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Retrato de Ca??izares
(2012-12-13)
Intracellular Ca2+ oscillations generated via the extracellular Ca2+-sensing receptor (CaSR) in response to extracellular Ca2+ or l-phenylalanine: Impact of the highly conservative mutation Ser170Thr
(Academic Press Inc Elsevier Science, 2015-11)
The extracellular Ca2+-sensing receptor (CaSR) is an allosteric protein that responds to changes in the extracellular concentration of Ca2+ ([Ca2+]e) and aromatic amino acids with the production of different patterns of ...
Localized nuclear and perinuclear Ca2+ signals in intact mouse skeletal muscle fibers
(Frontiers Media, 2015)
Nuclear Ca2+ is important for the regulation of several nuclear processes such as gene expression. Localized Ca2+ signals (LCSs) in skeletal muscle fibers of mice have been mainly studied as Ca2+ release events from the ...
Local and global Ca2+ signals: physiology and pathophysiology
(Sociedad de Biología de Chile, 2004)
Interplay between ER Ca2+ uptake and release fluxes in neurons and its impact on [Ca2+] dynamics
(Sociedad de Biología de Chile, 2004)
Tetracaine stimulates insulin secretion through the mobilization of Ca2+ from thapsigargin- and IP3-insensitive Ca2+ reservoir in pancreatic β-cells
(2000-01-01)
The effect of tetracaine on 45Ca efflux, cytoplasmic Ca2+ concentration [Ca2+](i), and insulin secretion in isolated pancreatic islets and β-cells was studied. In the absence of external Ca2+, tetracaine (0.1-2.0 mM) ...
Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888
(American Physiological Society, 2014-03)
To clarify the mechanism(s) underlying intracellular Ca2+ concentration ([Ca2+]i) oscillations induced by an elevation in extracellular Ca2+ concentration ([Ca2+]e) via the extracellular Ca2+-sensing receptor (CaR), we ...
Tetracaine stimulates insulin secretion through the mobilization of Ca2+ from thapsigargin- and IP3-insensitive Ca2+ reservoir in pancreatic beta-cells
(Natl Research Council Canada, 2000-06-01)
The effect of tetracaine on Ca-45 efflux, cytoplasmic Ca2+ concentration [Ca2+](i), and insulin secretion in isolated pancreatic islets and beta-cells was studied. In the absence of external Ca2+, tetracaine (0.1-2.0 mM) ...
Tetracaine stimulates insulin secretion through the mobilization of Ca2+ from thapsigargin- and IP3-insensitive Ca2+ reservoir in pancreatic beta-cells
(Natl Research Council Canada, 2000-06-01)
The effect of tetracaine on Ca-45 efflux, cytoplasmic Ca2+ concentration [Ca2+](i), and insulin secretion in isolated pancreatic islets and beta-cells was studied. In the absence of external Ca2+, tetracaine (0.1-2.0 mM) ...
The role of the Ca2+ binding ligand Asn879 in the function of the plasma membrane Ca2+ pump
(Elsevier Science, 2009-12)
Asn879 in the transmembrane segment M6 of the plasma membrane Ca2+ pump (PMCA human isoform 4xb) has been proposed to coordinate Ca2+ at the transport site through its carboxylate. This idea agrees with the fact that this ...