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Effects of the calpain inhibitor MDL28170 on the clinically relevant forms of Trypanosoma cruzi in vitro
(Oxford University Press, 2017)
Influência de inibidores proteicos e não-proteicos de proteases digestivas e caracterização bioquímico-cinética de cisteíno-proteases parcialmente purificadas de Anticarsia gemmatalisInfluence of proteinaceous and non-proteinaceous digestive protease inhibitors and kinetic biochemical characterization of cysteine-proteases partially purified of Anticarsia gemmatalis
(Universidade Federal de ViçosaBRBioquímica e Biologia molecular de plantas; Bioquímica e Biologia molecular animalDoutorado em Bioquímica AgrícolaUFV, 2015)
Cysteine proteases as digestive enzymes in parasitic helminths
(Public Library of Science, 2018)
In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases
(Fundación Revista Medicina, 2020)
Abstract/Resumen: Trypanosoma cruzi and Plasmodium falciparum are the etiologic agents of Chagas disease and Malaria, respectively. Cysteine proteases play key roles in the pathogenesis and survival of these parasites, ...
Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds
(WALTER DE GRUYTER & CO, 2009)
The inhibition of human cysteine cathepsins B, L, S and K was evaluated by a set of hypervalent tellurium compounds (telluranes) comprising both organic and inorganic derivatives. All telluranes studied showed a time-and ...
Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor
(Informa HealthcareLondon, 2013-08)
Cruzain is the major cysteine protease of Trypanosoma cruzi, the infectious agent responsible for Chagas disease, and cruzain inhibitors display considerable antitrypanosomal activity. In the present work we elucidated ...
Proteases inhibitors-insensitive cysteine proteases allow Nezara viridula to feed on growing seeds of field-grown soybean
(Pergamon-Elsevier Science Ltd, 2021-05)
The southern green stink bug, Nezara viridula is one of the primary soybean pests and causes significant economic losses around the world. In spite of the high proteases inhibitor (PI) levels, N. viridula can feed on ...