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Fibroblast growth factor 2 regulates cumulus differentiation under the control of the oocyte
(Springer, 2019-05-01)
PurposeWe first assessed regulation of FGF2 expression in cumulus cells by FSH and oocyte-secreted factors during in vitro maturation (IVM). Then, we tested the hypothesis that FGF2 regulates meiotic progression, cumulus ...
Interação YAP1-TEAD regula a cascata de sinalização do EGF em células do cumulus em bovinos
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2020-02-07)
The mechanism of cumulus cell (CC) expansion and ovulation in vivo is triggered by LH surge in granulosa cells and CC, which culminating in a series of paracrine and autocrine communications between these ovarian cells. ...
Time course of the meiotic arrest in sheep cumulus-oocyte complexes treated with roscovitine
(Cambridge University Press, 2015)
Temporary meiosis arrest with cyclin-dependent kinases inhibitors has been proposed in order to improve the quality of in vitro matured oocytes. In sheep, however, this phenomenon has been rarely investigated. Therefore, ...
Direct role of the C-C motif chemokine receptor 2/monocyte chemoattractant protein 1 system in the feline cumulus oocyte complex
(Society for the Study of Reproduction, 2019-04)
Studies were designed to a) evaluate the mRNA expression of the C-C motif chemokine receptor 2 (CCR2) and its chemokine ligands, as well as genes related to periovulatory events, within the cumulus oocyte complex (COC) and ...
Effects of fibroblast growth factor 8 on cumulus expansion and nuclear maturation in bovine cumulus-oocyte complexes
(CSIRO Publishing, 2013-01-01)
Immature oocyte quality and maturational competence of porcine cumulus-oocyte complex subpopulations
(Instituto de Histología y Embriología "Dr. Mario Burgos", 2009-12)
Porcine immature oocyte quality (i.e., that of live oocytes at the germinal vesicle stage) was evaluated according to features of the surrounding cumulus, aiming to establish maturational competence of different subpopulations ...
The importance of manganese in the cytoplasmic maturation of cattle oocytes: blastocyst production improvement regardless of cumulus cells presence during in vitro maturation
(Cambridge University Press, 2016-02)
Adequate dietary intake of manganese (Mn) is required for normal reproductive performance in cattle. This study was carried out to investigate the effect of Mn during in vitro maturation of bovine cumulus–oocyte complexes ...
Fibroblast growth factor 17 and bone morphogenetic protein 15 enhance cumulus expansion and improve quality of in vitro-produced embryos in cattle
(Elsevier B.V., 2015-08-01)
Bone morphogenetic protein 15 (BMP15) and members of the fibroblast growth factor (FGF) family are expressed by the oocyte and are involved in the control of cumulus cell function. We tested the hypothesis that FGF17, alone ...
Meiotic arrest of sheep oocytes using roscovitine under different medium compositions
(Elsevier B.V., 2015-05-01)
Attempts to maintain the meiotic arrest under suitable culture conditions have been performed in order to improve the quality of oocytes in vitro matured. So, our study aimed to evaluate the potential of roscovitine, an ...
Expresión de la proteína morfogénica ósea 15 (bmp-15) durante la maduración in vitro de ovocitos caninos
(Univ Zulia, Facultad Ciencias Veterinarias, 2016)
This research aims to characterize the pattern of expression of BMP-15 during in vitro maturation of canine oocyte. BMP-15 is a follicular factor related to the oocyte maturation, taking part in cumulus cells expansion and ...