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Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor
(2018)
The corticotropin-releasing factor (CRF) system is a key mediator of the stress response and addictive behavior. The CRF system includes four peptides: The CRF system includes four peptides: CRF, urocortins I-III, CRF ...
CRF binding protein facilitates the presence of CRF type 2 alpha receptor on the cell surface
(2016)
Corticotropin releasing factor binding protein (CRF-BP) was originally recognized as CRF sequestering protein. However, its differential subcellular localization in different brain nuclei suggests that CRF-BP may have ...
Corticotropin-releasing factor type-2 receptor and corticotropin-releasing factor-binding protein coexist in rat ventral tegmental area nerve terminals originated in the lateral hypothalamic area
(2016)
There is significant functional evidence showing that corticotropin-releasing factor type-2 receptor (CRF2R) and corticotropin-releasing factor-binding protein (CRF-BP) regulate glutamatergic synapses onto ventral tegmental ...
Ghrelin Indirectly Activates Hypophysiotropic CRF Neurons in Rodents
(Public Library of Science, 2012-02)
Ghrelin is a stomach-derived hormone that regulates food intake and neuroendocrine function by acting on its receptor, GHSR (Growth Hormone Secretagogue Receptor). Recent evidence indicates that a key function of ghrelin ...
Participação do fator de liberação de corticotrofina (CRF) no Locus coeruleus na resposta respiratória à hipercapnia
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2015-09-04)
Locus coeruleus (LC) is a pontine noradrenergic group that acts as a central chemoreceptor to CO2/pH and it is involved in the cognitive aspects of stress response and it is associated with a large number of physiological ...
CRF family peptides are differently altered by acute restraint stress and chronic unpredictable stress
(Elsevier B.V., 2014-09-01)
Corticotropin-releasing factor (CRF) acts to promote stress-like physiological and behavioral responses and is mainly expressed in the paraventricular hypothalamic nucleus (PVN). Urocortin 1 (Ucn1) is also a ligand to CRF ...