Buscar
Mostrando ítems 1-10 de 10
CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells
(ELSEVIER SCIENCE BV, 2008)
Ultraviolet (UV) light generates two major DNA lesions: cyclobutane pyrimidine dimers (CPDs) and pyrimidine-(6-4)-pyrimidone photoproducts (6-4PPs), but the specific participation of these two lesions in the deleterious ...
Estudo do gene da fotoliase de tripanossomatídeos: expressão heteróloga do gene de Trypanosoma brucei EM Trypanosoma cruzi
(Universidade Federal de Minas GeraisUFMG, 2014-03-31)
The Trypanosoma cruzi and Trypanosoma brucei are the protozoa parasites that cause African and American trypanosomiasis. Both are characterized by the presence of a single flagellum, a kinetoplast, which is elongated and ...
First characterisation of a CPD-class I photolyase from a UV-resistant extremophile isolated from High-Altitude Andean Lakes
(Royal Society of Chemistry, 2014-05)
UV-resistant Acinetobacter sp. Ver3 isolated from High-Altitude Andean Lakes (HAAL) in Argentinean Puna, one of the highest UV exposed ecosystems on Earth, showed efficient DNA photorepairing ability, coupled to highly ...
UV Resistance and Photoreactivation of Extremophiles from High-Altitude Andean Lakes
(Elsevier, 2013-04)
He HAAL are natural laboratories for exploring and monitoring in situ interactions between the geophysical environment and the dynamics of biodiversity. Solar irradiation (including high UV-B doses) is without doubt the ...
Extremophilic Acinetobacter Strains from High-Altitude Lakes in Argentinean Puna: Remarkable UV-B Resistance and Efficient DNA Damage Repair
(Springer, 2012-09)
High-Altitude Andean Lakes (HAAL) of the South American Andes are almost unexplored ecosystems of shallow lakes. The HAAL are recognized by a remarkably high UV exposure, strong changes in temperature and salinity, and a ...
Genômica comparativa de um baculovírus isolado da lagarta praga Rachiplusia nu (Guenée) (Lepidoptera: noctuidae)
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2019-07-16)
We described a novel baculovirus isolated from the polyphagous insect pest Rachiplusia nu. The virus presented pyramidal-shaped occlusion bodies (OBs) with singly-embed nucleocapsids and a dose mortality response of 6.9 × ...
Defective transcription/repair factor IN recruitment to specific UV lesions in trichothiodystrophy syndrome
(AMER ASSOC CANCER RESEARCH, 2008)
Most trichothiodystrophy (TTD) patients present mutations in the xeroderma pigmentosum D (XPD) gene, coding for a subunit of the transcription/repair factor IIH (TFHH) complex involved in nucleotide excision repair (NER) ...
Forged under the Sun: Life and Art of Extremophiles from Andean Lakes
(Wiley Blackwell Publishing, Inc, 2016-01)
High-altitude Andean lakes (HAAL) are a treasure chest for microbiological research in South America. Their indigenous microbial communities are exposed to extremely high UV irradiation and to multiple chemical extremes ...
Selection and optimization of reference genes for RT-qPCR normalization: a case study in Solanum lycopersicum exposed to UV-B
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2021-03-22)
Quantitative RT- PCR is one of the most common methods to study gene expression in response to stress. Therefore, it is crucial to have suitable reference genes (RGs) for result normalization. Although several reports ...