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Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B-1 and B-2 receptor knockout mice
(Elsevier B.V., 2001-12-01)
Experiments were designed to investigate the rule of kinin B-1 and B-2 receptors in Freund's adjuvant (CFA)-induced inflammation and nociception responses by the use of B-1 and B-2 null mutant mice. Intradermal (i.d.) ...
The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide
(Frontiers Research Foundation, 2012-01-01)
Paracoccidioidomycosis (PCM), a common chronic mycosis in Latin America, is a granulomatous systemic disease caused by the thermo-dimorphic fungus Paracoccidioides brasiliensis. the glycoprotein gp43 is the main antigen ...
Immune response induced by new adjuvant strategy to produce crotalic anti-PLA2
(Elsevier, 2019)
Snake envenomation is a serious medical problem and antivenoms are the main treatment. Antisera are produced by immunization of horses with snake venom using complete Freund's adjuvant and incomplete (booster) but it causes ...
IMT504 Provides Analgesia by Modulating Cell Infiltrate and Inflammatory Milieu in a Chronic Pain Model
(Springer, 2020-11)
IMT504 is a non-CPG, non-coding synthetic oligodeoxinucleotide (ODN) with immunomodulatory properties and a novel inhibitory role in pain transmission, exerting long-lasting analgesic effects upon multiple systemic ...
Antinociceptive and Anti-inflammatory Effects of the Hydroalcoholic Fraction from Leaves of Cenostigma macrophyllum Tul. var. acuminata Teles Freire (Leguminosae) in Rodents
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASUFMG, 2017)
Introdução: Cenostigma macrophyllum Tul. var. acuminata Teles Freire (Leguminosae) é conhecida localmente como “caneleiro” e suas cascas, folhas
e as flores são usadas na medicina popular contra distúrbios estomacais e ...
Antihyperalgesic Activity of Quillaic Acid Obtained from Quillaja saponaria Mol.
(BENTHAM SCIENCE PUBL LTD, 2019)
Background: Quillaja saponaria Mol. bark contains a high concentration of triterpene saponins that have been used for centuries as a cleansing, anti-inflammatory and analgesic agent in Chilean folk medicine. In earlier ...
Imunogenicidade de proteínas recombinantes da superfície do merozoíta de Plasmodium vivax candidatas à vacina contra malária.
(Universidade Federal de São Paulo (UNIFESP), 2006-01-01)
The aim of this study was to evaluate in a murine model, the capacity of the helper epitope PADRE (Pan Allelic DR epitope) to improve the immunizations with the P. vivax MSP119 in the presence of distinct adjuvant formulations. ...
A recombinant vaccine based on domain II of Plasmodium vivax Apical Membrane Antigen 1 induces high antibody titres in mice
(ELSEVIER SCI LTD, 2010)
The Apical Membrane Antigen 1 (AMA-1) is considered a promising candidate for development of a malaria vaccine against asexual stages of Plasmodium. We recently identified domain II (DII) of Plasmodium vivax AMA-1 (PvAMA-1) ...