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When does the mammalian GPS use the dentate gyrus in everyday challenges of spatial navigation?
(SAGE Publications, 2020)
Our mammalian GPS, Global Positioning System, is made of diverse brain structures such as the dentate gyrus (DG) of the hippocampus. This is one of the most plastic brain regions because it has adult neurogenesis and this ...
Nitric oxide modulation of methylphenidate-induced disruption of prepulse inhibition in Swiss mice
(ELSEVIER SCIENCE BV, 2009)
Drugs that facilitate dopaminergic neurotransmission induce cognitive and attentional deficits which include inability to filter sensory input measured by prepulse inhibition (PPI) Methylphenidate, an amphetamine analog ...
Toward an Explanation of the Genesis of Ketamine-Induced Perceptual Distortions and Hallucinatory States
(2003-12-01)
The NMDA receptor (NMDAR) channel has been proposed to function as a coincidence-detection mechanism for afferent and reentrant signals, supporting conscious perception, learning, and memory formation. In this paper we ...
Toward an Explanation of the Genesis of Ketamine-Induced Perceptual Distortions and Hallucinatory States
(2003-12-01)
The NMDA receptor (NMDAR) channel has been proposed to function as a coincidence-detection mechanism for afferent and reentrant signals, supporting conscious perception, learning, and memory formation. In this paper we ...
Nitric oxide synthase inhibitors improve prepulse inhibition responses of Wistar rats
(ELSEVIER SCIENCE BV, 2011)
Introduction: Cognitive and attentional deficits in schizophrenia include impairment of the sensorimotor filter as measured by prepulse inhibition (PPI). In this way, the study of animals that naturally present low PPI ...
Oxidación de aminas psicotrópicas mediada por especies reactivas del oxígeno y su relevancia farmacológica
(Universidad de Chile, 2009)
Numerosas publicaciones demuestran la asociación de diversas patologías del SNC a estrés oxidativo. En estas condiciones, los neurotransmisores como las catecolaminas y la serotonina, y fármacos como la cimetidina, sufren ...
Acute Chemogenetic Inhibition of Caudal NTS Astrocytes Reduced Systemic Blood Pressure in Rats Exposed to Chronic Intermittent Hypoxia-mimicking Sleep Apnea Syndrome
(NLM (Medline), 2022)
© FASEB.Chronic intermittent hypoxia (CIH), the main feature of obstructive sleep apnea, enhances carotid body (CB) discharges, leading to heightened sympathetic outflow and systemic hypertension. Previously, we found that ...