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WBC count and functional changes induced by co-administration of clofazimine and clarithromycin, in single and multiple doses, in Wistar rats

Paina, Flavia Aparecida; Miranda, Julise Cunha; de Freitas Tavares, Cristiane Fernandes; da Costa Queiroz, Regina Helena; de Souza, Ana Maria (UNIV SAO PAULO, CONJUNTO QUIMICASSAO PAULO, 2012)

Clofazimine and clarithromycin are used to treat leprosy and infections caused by Mycobacterium avium complex. Little data on the toxicity of co-administration of these two drugs are available. Here we evaluated the potential ...