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The structure and evolution of cisregulatory regions: The shavenbaby story
(The Royal Society, 2013-12)
In this paper, we provide a historical account of the contribution of a single line of research to our current understanding of the structure of cis-regulatory regions and the genetic basis for morphological evolution. We ...
Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during early Drosophila development
(Nature Publishing Group, 2021-04)
Acquisition of cell fate is thought to rely on the specific interaction of remote cis-regulatory modules (CRMs), for example, enhancers and target promoters. However, the precise interplay between chromatin structure and ...
Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene
(2014)
Background: Human RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; ...
Comparative Genomics, Evolution, and Drought-Induced Expression of Dehydrin Genes in Model Brachypodium Grasses
(MDPI, 2021-12)
Dehydration proteins (dehydrins, DHNs) confer tolerance to water-stress deficit in plants. We performed a comparative genomics and evolutionary study of DHN genes in four model Brachy-podium grass species. Due to limited ...
Estructura y función de la región regulatoria de la transcripción del gen shavenbaby en Drosophila melanogasterStructure and function of the cis-regulatory of shavenbaby gene in Drosophila melanogaster
(2018-03-16)
Los programas genéticos del desarrollo en organismos multicelulares son regulados por cambios en la expresión génica. Estos cambios determinan los procesos de diferenciación celular que suceden durante el desarrollo de los ...
Cracking the genome's second code: Enhancer detection by combined phylogenetic footprinting and transgenic fish and frog embryos
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07)
Genes involved in vertebrate development are unusually enriched for highly conserved non-coding sequence elements. These regions are readily detected in silico, by genome-wide sequence comparisons between different ...
Combinatorial regulation modules on GmSBP2 promoter: a distal cis-regulatory domain confines the SBP2 promoter activity to the vascular tissue in vegetative organs
(Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2018)
Cracking the genome's second code: Enhancer detection by combined phylogenetic footprinting and transgenic fish and frog embryos
(2006)
Genes involved in vertebrate development are unusually enriched for highly conserved non-coding sequence elements. These regions are readily detected in silico, by genome-wide sequence comparisons between different ...