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Unique thermal behavior of sphingomyelin species with nonhydroxy and 2-hydroxy very-long-chain (C28-C32) PUFAs
(American Society for Biochemistry and Molecular Biology, 2013-05)
In rat germ cells and spermatozoa, sphingomyelin (SM) contains molecular species with nonhydroxy (n) and 2-hydroxy (h) very-long-chain polyunsaturated fatty acids (V), the most abundant being SMs with (n- and h-) 28:4n-6, ...
Differential involvement of rat sperm choline glycerophospholipids and sphingomyelin in capacitation and the acrosomal reaction
(Elsevier France-editions Scientifiques Medicales Elsevier, 2010-12)
Rat spermatozoa main lipid classes and their fatty acids were studied to assess their possible changes in capacitation and the acrosomal reaction (AR), induced in vitro . Capacitation-associated protein tyrosine phosphorylation, ...
Impact of sphingomyelin acyl chain (16:0 vs 24:1) on the interfacial properties of Langmuir monolayers: a PM-IRRAS study
(Elsevier Science, 2019-01)
Membrane structure is a key factor for the cell`s physiology, pathology, and therapy. Evaluating the importance of lipid species such as N-nervonoyl sphingomyelin (24:1-SM) —able to prevent phase separation— to membrane ...
Novel evidence for the specific interaction between cholesterol and α-haemolysin of Escherichia coli
(Portland Press, 2014-03)
Several toxins that interact with animal cells present some kind of interaction with cholesterol (Cho) or sphingomyelin. In the present work we demonstrate that alpha hemolysin of E. coli (HlyA) interacts directly with ...
Cholesterol modulates curcumin partitioning and membrane effects
(2018-01-01)
Curcumin, a polyphenol molecule, presents a wide range of biological activities as antioxidant, anticancer, anti-inflammatory, antimicrobial and wound healing. Although some strengths attributed to curcumin derive from ...
The lipid composition of a cell membrane modulates the interaction of an antiparasitic peptide at the air-water interface
(Elsevier B.V., 2011-07-01)
The antiparasitic property of peptides is believed to be associated with their interactions with the protozoan membrane, which calls for research on the identification of membrane sites capable of peptide binding. In this ...
Quercetin induces lipid domain-dependent permeability
(2022-01-01)
Quercetin is a polyphenolic molecule with a broad spectrum of biological activities derived from its antioxidant property. Its mechanism of action has been explained by its binding and/or interference with enzymes, receptors, ...