Buscar
Mostrando ítems 1-10 de 296
Cc2d1a, a C2 domain containing protein linked to nonsyndromic mental retardation, controls functional maturation of central synapses
(American Physiological Society, 2011-04)
Cc2d1a is an evolutionarily conserved protein composed of NH2-terminal Drosophila melanogaster 14 domain (DM14) domains and a COOH-terminal C2 domain. Human patients with homozygotic mutation in the gene suffer from ...
Synaptic dimorphism in Onychophoran cephalic ganglia
(Universidad de Costa Rica, 2007)
Structure-function implications in ALzheimer´s disease: Effect of Ab oligomers at Central Synapses
(2008)
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A characteristic of AD is the accumulation of plaques in the brain of AD patients, and theses plaques ...
Relationship between Na+, K+-ATPase and NMDA receptor at central synapses
(Bentham Science Publishers, 2014-08)
Specific receptors for classical neurotransmitters and neuropeptides, as well as the Na+, K+-ATPase, are all molecular entities inserted into synaptic region membranes and localized contiguously. Herein, available experimental ...
The endothelial nitric oxide synthase isoform is present in neuronal synapses and lipid rafts.
(2015)
Nitric oxide (NO) modulates several processes in the central nervous system while its increase in oxidative stress conditions is associated to neuronal damage. Its synthesis in the brain has been most commonly been ascribed ...
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity
(Sociedad de Biología de Chile, 2011)
A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy
(Natl Acad SciencesWashingtonEUA, 2004)
Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior
(2019)
Neurodevelopmental disorders offer insight into synaptic mechanisms. To unbiasedly uncover these mechanisms, we studied the 22q11.2 syndrome, a recurrent copy number variant, which is the highest schizophrenia genetic risk ...