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Immune response to cytolethal distending toxin of Aggregatibacter actinomycetemcomitans in periodontitis patients
(WILEY-BLACKWELL, 2010)
Background and Objective: Cytolethal distending toxin (CDT) is a genotoxin produced by Aggregatibacter actinomycetemcomitans. In spite of its association with pathogenesis, little is known about the humoral immune response ...
Immune response to cytolethal distending toxin of Aggregatibacter actinomycetemcomitans in periodontitis patients
(Wiley-Blackwell, 2010-08-01)
Background and Objective:Cytolethal distending toxin (CDT) is a genotoxin produced by Aggregatibacter actinomycetemcomitans. in spite of its association with pathogenesis, little is known about the humoral immune response ...
Investigation of putative CDT gene in Escherichia coli isolates from pigs with diarrhea
(Elsevier Science BvAmsterdamHolanda, 2002)
The cytolethal distending toxin of Aggregatibacter actinomycetemcomitans inhibits macrophage phagocytosis and subverts cytokine production
(Academic PressSão Diego, 2014-03)
Aggregatibacter actinomycetemcomitans is an important periodontal pathogen that can participate in periodontitis and other non-oral infections. The cytolethal distending toxin (Cdt) is among the virulence factors produced ...
Selection of nanobodies that block the enzymatic and cytotoxic activities of the binary Clostridium difficile toxin CDT
(Nature Publishing Group, 2015-01)
The spore-forming gut bacterium Clostridium difficile is the leading cause of antibiotic-associated diarrhea in hospitalized patients. The major virulence factors are two large glucosylating cytotoxins. Hypervirulent strains ...