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Expresión de CD40 y CD40L en pacientes con artritis reumatoide y su asociación con la actividad clínica evaluada por el DAS28
(Biblioteca Digital wdg.biblioUniversidad de Guadalajara, 2018-01-25)
Introducción: La artritis reumatoide (AR) es una enfermedad autoinmune inflamatoria
crónica que afecta las articulaciones periféricas. La vía de coestimulación mediada por el
receptor CD40 y su ligando, CD40L, participa ...
Análisis de variantes genéticas de CD40 y CD40L, expresión relativa del mRNA y cuantificación de las formas solubles: estudio de asociación en pacientes con síndrome coronario agudo
(Biblioteca Digital wdg.biblioUniversidad de Guadalajara, 2020-02-21)
Introducción: El síndrome coronario agudo (ACS) es el conjunto de los síntomas resultantes de un evento isquémico cardiaco, caracterizado por la obstrucción parcial o total de una arteria coronaria. Dentro de la etiología ...
No evidence for association of the CD40, CD40L and BLYS polymorphisms, B-cell co-stimulatory molecules, with Brazilian endemic Plasmodium vivax malaria
(2013-06-01)
Background: Plasmodium vivax is the most prevalent malaria species in Brazil. The parasite-host coevolutionary process can be viewed as an 'arms race', in which adaptive genetic changes in one are eventually matched by ...
No evidence for association of the CD40, CD40L and BLYS polymorphisms, B-cell co-stimulatory molecules, with Brazilian endemic Plasmodium vivax malaria
(2013-06-01)
Background: Plasmodium vivax is the most prevalent malaria species in Brazil. The parasite-host coevolutionary process can be viewed as an 'arms race', in which adaptive genetic changes in one are eventually matched by ...
Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice
(Schattauer Gmbh-Verlag Medizin Naturwissenschaften, 2014-08)
The co-stimulatory immune molecule CD40L figures prominently in a variety of inflammatory conditions including arterial disease. Recently, we made the surprising finding that CD40L mediates atherogenesis independently of ...
Avaliação dos níveis séricos de sCD40, sCD40L e S4-1BB na insuficiência cardíaca avançada e após o transplante cardíaco
(Universidade Federal de São Paulo (UNIFESP), 2017-12-20)
Heart failure is one of the most important problems in public health. Although big advances had been reached in treatment, the prognosis of advanced heart failure is still reserved and the heart transplant is the main ...
CD34-positive cells and their subpopulations characterized by flow cytometry analyses on the bone marrow of healthy allogenic donors
(Associação Paulista de Medicina - APM, 2009-01-01)
CONTEXT AND OBJECTIVE: Counting and separating hematopoietic stem cells from different sources has importance for research and clinical assays. Our aims here were to characterize and quantify hematopoietic cell populations ...
Distribution of naive and memory/effector CD4+ T lymphocytes and expression of CD38 on CD8+ T lymphocytes in AIDS patients with tuberculosis
(Brazilian Society of Infectious Diseases, 2003-04-01)
CD4+ and CD8+ T lymphocyte counts, naive and memory/effector CD4+ T subpopulations, and the expression of CD38 on CD8+ T lymphocytes were evaluated in four groups: AIDS patients with tuberculosis (HIV/TB, n=14), HIV-1 ...
Angiotensin II modulates CD40 expression in vascular smooth muscle cells
(PORTLAND PRESS LTD, 2009)
The signalling pathway CD40/CD40L (CD40 ligand) plays an important role in atherosclerotic plaque formation and rupture. AngII (angiotensin II), which induces oxidative stress and inflammation, is also implicated in the ...