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CD39 expression defines cell exhaustion in tumor-infiltrating CD8+ T cells
(American Association for Cancer Research, 2018-01-24)
The ability of CD8+ T lymphocytes to eliminate tumors is limited by their ability to engender an immunosuppressive microenvironment. Here we describe a subset of tumor-infiltrating CD8+ T cells marked by high expression ...
La bitácora
(Universidad Católica de Pereira, 2007)
B cells from patients with rheumatoid arthritis show conserved CD39-mediated regulatory function and increased CD39 expression after positive response to therapy
(Academic Press Ltd - Elsevier Science Ltd, 2021-01)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by progressive joint destruction associated with increased pro-inflammatory mediators. In inflammatory microenvironments, exogenous ATP (eATP) is ...
CD39 as a marker of pathogenic CD8+ T cells in cancer and other chronic inflammatory diseases
(Impact Journals, 2018-04)
CD8+ T cells have long been considered crucial in the immune response against tumors. However, in the last decade a subpopulation of exhausted CD8+ T cells has been described which exhibit a dysfunctional phenotype and ...
El house keeping y el layout en Tacones Diana Sector Industria Manufacturera (Calzado)
(Universidad Católica de Pereira, 2005)
CD39 delineates cell exhaustion in human and mouse tumor-infiltrating CD8+ T cells
(American Association for Cancer Research, 2017-10)
The ability of CD8+ T lymphocytes to eliminate tumors is limited by their ability to engender an immunosuppressive microenvironment. Here we describe a subset of tumor-infiltrating CD8+ T cells marked by high expression ...
Estudio fenotípico y funcional de linfocitos T CD8+ Cd39+ en el contexto de la respuesta inmune antitumoral
(2018-01-01)
Las células tumorales poseen diversos mecanismos para evadir la respuesta inmune antitumoral gatillada por células de la inmunidad innata, como las células asesinas naturales (NK, del ingés Natural Killers), y de la inmunidad ...
Expansion in CD39(+) CD4(+) Immunoregulatory T Cells and Rarity of Th17 Cells in HTLV-1 Infected Patients Is Associated with Neurological Complications
(Public Library Science, 2013-02-01)
HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It is unclear why a minority of infected ...
Notch signalling regulates cytokine production by cd8+ and cd4+ t cells
(WILEY-BLACKWELL, 2012)