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Raquitismo vitamina D dependiente tipo I
(Sociedad Uruguaya de Pediatría, 2006)
Efecto estimulador del calcitriol a través del receptor de la vitamina D en la expresión génica y secreción de la prolactina de origen linfocitario
(2011-09-22)
Prolactin is a protein hormone that is produced by the pituitary lactotrophs and also
by extrapituitary sites such as decidua and lymphocytes. Calcitriol, the active form
of vitamin D3, is a secosteroid with immunomodulatory ...
Efecto del calcitriol sobre la sintesis placentaria de citocinas pro- nflamatorias en la preeclampsia y regulación de CYP27B1 y CYP24A1 por TNF-IFN- IL-6 e IL -1
(2011-09-22)
Placenta is an important source and target of hormones that contribute to
immunological tolerance in pregnancy. It is known that in preeclampsia (PE), the
placenta 1,25-dihydroxyvitamin D3 (calcitriol) synthesis is low; ...
Calcitriol oral pulse therapy in children with renal osteodystrophy
(Springer-Verlag, 1995)
A 6-month protocol of oral pulse calcitriol was used in nine uraemic children (2-14 years old) on dialysis who presented with renal osteodystrophy. Calcitriol was administered twice a week, 4 μg per dose for patients over ...
Efeitos supressivo do calcitriol sobre a produção do paratormônio em pacientes com hiperparatiroidismo secundário à insuficiência renal crônica
(Universidade Federal de São Paulo (UNIFESP), 1994)
Calcitriol decreases HIV-1 transfer in vitro from monocyte-derived dendritic cells to CD4 + T cells, and downregulates the expression of DC-SIGN and SIGLEC-1
(Public Library of ScienceInmunovirologíaSan Francisco, Estados Unidos, 2022)
Novel calcitriol analogue with an oxolane group: In vitro, in vivo, and in silico studies
(Wiley VCH Verlag, 2019-04-26)
The active form of vitamin D3, calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. ...
Vitamin D receptor exhibits different pharmacodynamic features in tumoral and normal microenvironments: A molecular modeling study
(Pergamon-Elsevier Science Ltd, 2020-03-03)
The vitamin D receptor (VDR) constitutes a promising therapeutic target for the treatment of cancer. Unfortunately, its natural agonist calcitriol does not have clinical utility due to its potential to induce hypercalcemic ...
The alkynylphosphonate analogue of calcitriol EM1 has potent anti-metastatic effects in breast cancer
(Pergamon-elsevier Science Ltd, 2015-09)
The active form of vitamin D3, calcitriol, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and prodifferentiating agent. However, when effective antitumor doses ...