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Understanding the role of the blood brain barrier and peripheral inflammation on behavior and pathology on ongoing confined cortical lesions
(Elsevier, 2021-11)
Background: Inflammation in the Central Nervous System (CNS) is associated with blood brain barrier (BBB) breakdown during the early stages of Multiple Sclerosis (MS), indicating a facilitated entry of waves of inflammatory ...
Leishmania hide-and-seek: Parasite amastigotes in the choroid plexus of a dog with neurological signs in an endemic municipality in Brazil
(2019-08-01)
A female adult mixed-breed stray dog presented with hind limb paraparesis and clinical signs of visceral leishmaniasis. The cerebrospinal fluid presented signs of blood-brain barrier disruption. Both spleen and brain were ...
Brain vasculature disturbance in schizophrenia
(Lippincott Williams & Wilkins, 2022)
Purpose of review The vascular hypothesis of schizophrenia (SZ) postulates that brain endothelial dysfunction contributes to brain pathophysiology. This review discusses recent evidence for and against this hypothesis, ...
Cognitive Impairment and Inflammation in Old Age and the Role of Modifiable Risk Factors of Neurocognitive Disorders
(Frontiers Research Foundation, 2022)
Perinatal inflammation and adult psychopathology: From preclinical models to humans
(Academic Press Ltd - Elsevier Science Ltd, 2018-05)
Perinatal environment plays a crucial role in brain development and determines its function through life. Epidemiological studies and clinical reports link perinatal exposure to infection and/or immune activation to various ...
Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis
(Public Library of Science, 2015)
Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. ...
Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis
(Public Library of Science, 2015)
BACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. ...
Disruption of the blood-brain barrier in pigs naturally infected with Taenia solium, untreated and after anthelmintic treatment
(Elsevier, 2013)
Neurocysticercosis is a widely prevalent disease in the tropics that causes seizures and a variety into of neurological symptoms in most of the world. Experimental models are limited and do not allow assessment of the ...
Neurocysticercosis: A natural human model of epileptogenesis
(Wiley, 2015)
Objective: To develop a better understanding of mechanisms of seizures and long-term epileptogenesis using neurocysticercosis. Methods A workshop was held bringing together experts in epilepsy and epileptogenesis and ...