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CrataBL, a lectin and Factor Xa inhibitor, plays a role in blood coagulation and impairs thrombus formation
(Walter De Gruyter Gmbh, 2014-09-01)
Arterial thrombosis is an important complication of diabetes and cancer, being an important target for therapeutic intervention. Crataeva tapia bark lectin (CrataBL) has been previously shown to have hypoglycemiant effect ...
Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors
(Taylor & Francis Inc, 2019-04-03)
The purpose of antithrombotic therapy is the prevention of thrombus formation and/or its extension with a minimum risk of bleeding. The inhibition of a variety of proteolytic processes, particularly those of the coagulation ...
CrataBL, a lectin and Factor Xa inhibitor, plays a role in blood coagulation and impairs thrombus formation
(Walter De Gruyter Gmbh, 2015)
Proteinase inhibitors in Brazilian leguminosae
(Instituto Oswaldo Cruz, Ministério da Saúde, 1991-01-01)
Serine proteinase inhitors, in the seeds of several Leguminosae from the Pantanal region (West Brazil), were studied using bovine trypsin, a digestive enzyme, Factor XIIa and human plasma Kallikrein, two blood clotting ...
Coagulation Factor XII Gene Mutation in Brazilian Families with Hereditary Angioedema with Normal C1 Inhibitor
(Karger, 2015-01-01)
Background: Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH) is a rare disorder. Mutations of the gene encoding coagulation factor XII have been identified in a subset of patients with this condition. Our aim ...
Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein
(American Heart AssociationDallas, 2013-06)
BACKGROUND:
Generation of active procoagulant cofactor factor Va (FVa) and its subsequent association with the enzyme activated factor X (FXa) to form the prothrombinase complex is a pivotal initial event in blood coagulation ...
Genetic markers associated with complications of hemophilia: A scoping review
(Universidade Federal de Juiz de Fora - Campus Avançado de Governador ValadaresBrasilICV - Instituto de Ciências da VidaUFJF/GV, 2022)
Bacterias lácticas inmunomoduladoras en la regulación en la regulación de las alteraciones hemostáticas inducidas durante una infección respiratoria en huésped inmunosuprimido por desnutrición. Mecanismos básicos de acciónImmunomodulatory lactic acid bacteria in regulation of haemostatic alterations induced during a respiratory infection in immunosuppressed host by malnourishment. Basic mechanisms of action
(Médicas del Sur, 2013)
Malnutrition induces a decrease in immunity that affects the ability of the organism to deal with an infectious challenge. The clotting system is considered a branch of immunity and its activation is important in the ...