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Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function
(FUTURE MEDICINE LTD, 2010)
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a consequence, BDNF has become a key ...
Neuroprogresión y cognición en los trastornos bipolares: una revisión sistemática del rendimiento cognitivo en pacientes eutímicosNeuroprogression and cognition in bipolar disorders: a systematic review of cognitive performance in euthymic patients
(Polemos, 2015-08)
En los últimos años, distintos investigadores comenzaron a considerar la posibilidad de explicar la fisiopatología del trastorno bipolar desde una perspectiva neuroprogresiva. Las evidencias que respaldan la factibilidad ...
Relação entre as alterações estruturais do cerebelo e os transtornos psiquiátricos
(Universidade Federal de São Paulo (UNIFESP), 2011-06-29)
Classically it was attributed to the cerebellum only functions regarding the control of movements, posture and balance. However, several studies have shown that the cerebellum also participates in the control of cognition, ...
A inibição da recaptação de dopamina pelo GBR12909 como um possível modelo animal de mania: aspectos comportamentais, farmacológicos e neuroimunológicos
(Universidade Federal de Minas GeraisUFMG, 2015-12-01)
Bipolar disorder (BD) is a psychiatric disorder featured by the occurrence of mania and depression episodes. The pharmacological treatment consists in mood stabilizers, including lithium and valproate. In addition, ...
Platelet GSK3B activity in patients with late-life depression: Marker of depressive episode severity and cognitive impairment?
(INFORMA HEALTHCARE, 2011)
Objective. Increased GSK3B activity has been reported as a state marker of major affective episodes in patients with depression and bipolar disorder. No study so far has addressed GSK3B activity in late-life depression. ...
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis
(BLACKWELL PUBLISHING, 2008)
Purpose: As reported by several authors, angiotensin II (AngII) is a proinflammatory molecule that stimulates the release of inflammatory cytokines and activates nuclear factor kappa B (NF kappa B), being also associated ...
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis
(Blackwell Publishing, 2008-08-01)
Purpose: As reported by several authors, angiotensin II (AngII) is a proinflammatory molecule that stimulates the release of inflammatory cytokines and activates nuclear factor kappa B (NF kappa B), being also associated ...
Participação do sistema endocanabinóide em respostas comportamentais induzidas pela inibição do transportador de dopamina
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FARMACOLOGIAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2020-06-23)
Dopamine transpoter (DAT) inhibition induces behavioral changes in animals that can be related to maniac state of Bipolar Disorder (BD) in humans. Due that is an important tool for elucidate the physiopathology of BD. The ...