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Physics at the biomolecular interface : fundamentals for molecular targeted therapy
(Springer, 2016)
This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the ...
Biomolecular interfaces: interactions, functions and drug design
(Springer, 2015)
The book deals with a largely overlooked area of molecular biophysics that is likely to have strong impact on molecularly targeted medicine and drug design: the aqueous interface of a soluble protein. Foundational knowledge ...
Packing defects functionalize soluble proteins
(Wiley, 2015-03)
This work explores the participation of protein packing defects, the so-called dehydrons, in biochemical events. We delineate the enabling role of dehydrons as activators of nucleophilic groups. This activation results ...
Non-Debye frustrated hydration steers biomolecular association: interfacial tension for the drug designer
(Wiley, 2016-10)
Many cellular functions involve the assembly of biomolecular complexes, a process mediated by water that gets displaced as subunits bind. This process affects water frustration, that is, the number of unmet hydrogen-bonding ...
Zwitterionic Silane Copolymer for Ultra-Stable and Bright Biomolecular Probes Based on Fluorescent Quantum Dot Nanoclusters
(American Chemical Society, 2017-05)
Fluorescent semiconductor quantum dots (QDs) exhibit several unique properties that make them suitable candidates for biomolecular sensing, including high brightness, photostability, broad excitation, and narrow emission ...
Computational framework to support integration of biomolecular and clinical data within a translational approach
(2013-06-06)
Abstract
Background
The use of the knowledge produced by sciences to promote human health is the main goal of translational medicine. To make it feasible we need computational ...
Computational framework to support integration of biomolecular and clinical data within a translational approach
(2013-06-06)
Abstract
Background
The use of the knowledge produced by sciences to promote human health is the main goal of translational medicine. To make it feasible we need computational ...
Computational framework to support integration of biomolecular and clinical data within a translational approach
(BioMed CentralLondon, 2013)
Background
The use of the knowledge produced by sciences to promote human health is the main goal of translational medicine. To make it feasible we need computational methods to handle the large amount of information that ...
Desenvolvimento de candidatos a fármacos para tratamento da Leucemia Mielóide Crônica a partir do Imatinibe
(Universidade Federal do ParáBrasilInstituto de Ciências da SaúdeUFPAPrograma de Pós-Graduação em Química Medicinal e Modelagem Molecular, 2022)
Bromide counterion as a spectroscopic sensor at the interface of cetyltrimethylammonium micelles
(Pergamon-Elsevier Science Ltd, 2019-12-05)
The strong UV absorption of the bromide in aqueous solution undergoes a remarkable red shift of more than 10 nm induced by the addition of the salts that constitute a saline buffer. The maximum absorption wavelength of the ...