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Computational Detection of MicroRNA Targets
(2022-01-01)
MicroRNAs (miRNAs) are small noncoding RNAs that are recognized as posttranscriptional regulators of gene expression. These molecules have been shown to play important roles in several cellular processes. MiRNAs act on ...
Advancements in the co-formulation of biologic therapeutics
Biologic therapeutics are the medicines of the future and are destined to transform the approaches
by which the causes and symptoms of diseases are cured and alleviated. These approaches will
be accelerated through the ...
Distorted wave calculations fpr electron loss process induced by bare ion impact on biological targets
(Elsevier, 2014-01)
Distorted wave models are employed to investigate the electron loss process induced by bare ions on biological targets. The two main reactions which contribute to this process, namely, the single electron ionization as ...
Novel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches
(Springer New York LLC, 2016)
Insight into nanoparticle cellular uptake and intracellular targeting
(2014)
Collaborative efforts from the fields of biology, materials science, and engineering are leading to exciting progress in the development of nanomedicines. Since the targets of many therapeutic agents are localized in ...
Publisher Correction: Pharmacological targeting of the unfolded protein response for disease intervention (Nature Chemical Biology, (2019), 15, 8, (764-775), 10.1038/s41589-019-0326-2)
(Nature Publishing Group, 2019)
© 2019, Springer Nature America, Inc.An amendment to this paper has been published and can be accessed via a link at the top of the paper.
The efficiency of multi-target drugs: A network approach
(Springer, 2020)
Multi-target agents have attracted great attention in the last 15 years, as they are expected to provide more efficacious and safer therapeutic solutions, less prone to drug resistance phenomena. They thus seem particularly ...
Network pharmacology and epilepsy
(Springer, 2016)
In contrast with the reductionist “one gene, one target, one drug” approach, network pharmacology proposes the use of multi-target therapies, a strategy that seems particularly suitable to treat disorders of complex etiology, ...
Molecular Biology for Anti-Trypanosomatid Drug Discovery and Target Elucidation.
(Nova Science Publishers Inc, 2022)
Repression: Targeting the heart of the matter
(Cell Press, 1999)