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Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis
(BMC, 2019)
BackgroundAmyotrophic lateral sclerosis (ALS) is a multifactorial fatal motoneuron disease without a cure. Ten percent of ALS cases can be pointed to a clear genetic cause, while the remaining 90% is classified as sporadic. ...
Contributions of bioinformatics to study natural antifungals: review in a pharmacological context
(Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde, 2021)
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
(ELSEVIER SCIENCE INC, 2018)
The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
Bioinformatic prediction of polymerase elements in the rotavirus VP1 protein
(Sociedad de Biología de Chile, 2006)
NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family
(ELSEVIER, 2020)
Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary stroke disorder caused by mutations in the NOTCH3 gene. We report the first Chilean ...
How bioinformatics enables livestock applied sciences in the genomic era
(2012-09-05)
This review paper presents the three main approaches currently used in livestock genomic sciences where the bioinfomatics plays a critical role. They are named as Genomic Selection (GS), Genome Wide Association Study (GWAS) ...
How bioinformatics enables livestock applied sciences in the genomic era
(2012-09-05)
This review paper presents the three main approaches currently used in livestock genomic sciences where the bioinfomatics plays a critical role. They are named as Genomic Selection (GS), Genome Wide Association Study (GWAS) ...
The Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America
(Hindawi Publishing Corporation, 2016)
Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis
(FRONTIERS MEDIA SA, 2019)
Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. It has been suggested that P salmonis is able to survive in host macrophages, ...
Bacterially produced metabolites protect C. elegans neurons from degeneration
(Public Library of Science, 2020-03)
Caenorhabditis elegans and its cognate bacterial diet comprise a reliable, widespread model to study diet and microbiota effects on host physiology. Nonetheless, how diet influences the rate at which neurons die remains ...