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Adaptive regulation of hepatic bile salt transport: Role of bile salt hydrophobicity and microtubule-dependent vesicular pathway
(MUNKSGAARD INT PUBL LTD, 1997)
Background/Aims: The hepatic transport of bile salts can be regulated by changes in bile salt pool size and/ or in the flux of bile salts through the liver, Prolonged bile salt pool depletion is associated with down-regulation ...
New insights into bacterial bile resistance mechanisms: the role of bile salt hydrolase and its impact on human health
(Elsevier Science, 2018-10)
Bile acids (BA), the major components of bile, are biological detergents that facilitate the emulsification and solubilization of dietary lipids and also display potent antimicrobial activity, the bacterial membranes being ...
ADAPTIVE REGULATION OF HEPATIC BILE-SALT TRANSPORT - EFFECTS OF ALLOXAN DIABETES IN THE RAT
(W B SAUNDERS CO, 1991)
The hepatic transport of bile salts appears to be adaptively regulated by changes in the bile salt pool size and in the flux of bile salt through the liver. The maximum secretory rate of taurocholate increases or decreases ...
ASSOCIATION OF CANALICULAR MEMBRANE ENZYMES WITH BILE-ACID MICELLES AND LIPID AGGREGATES IN HUMAN AND RAT BILE
(ELSEVIER SCIENCE BV, 1995)
This study was undertaken to gain insights into the characteristics of the polymolecular association between canalicular membrane enzymes, bile acids, cholesterol and phospholipids in bile and into the cellular mechanisms ...
Impact of bile salt adaptation of Lactobacillus delbrueckii subsp. lactis 200 on its interaction capacity with the gut
(Elsevier Science, 2011-10)
In a previous work, bile-salt-resistant derivatives were obtained from non-intestinal lactobacilli. The aim of this work was to investigate the impact of bile adaptation of Lactobacillus delbrueckii subsp. lactis 200 on ...
Bile salts and derivatives: Rigid unconventional amphiphiles as dispersants, carriers and superstructure building blocks
(2015)
Steroidal surfactants like bile salts have a rigid amphiphilic structure significantly different from the typical head–tail one. As a result, these molecules show peculiar features in their self-assembly behavior and ...
Aquaporin gene therapy for cholestasis
(John Wiley & Sons Inc, 2017-01)
This is regarding the editorial “Aquaporin gene therapy for disorders of cholestasis?” by Tradtrantip and Verkman.(1) We thank the authors for their comments in our recent studies.(2,3) Nevertheless, we believe that an ...
Studies on the interactions between bile salts and food emulsifiers under in vitro duodenal digestion conditions to evaluate their bile salt binding potential
(Elsevier Science, 2019-02)
During the last decade a special interest has been focused on studying the relationship between the composition and structure of emulsions and the extent of lipolysis, driven by the necessity of modulate lipid digestion ...
ENHANCED BILIARY-EXCRETION OF CANALICULAR MEMBRANE ENZYMES IN ETHYNYLESTRADIOL-INDUCED CHOLESTASIS - EFFECTS OF URSODEOXYCHOLIC ACID ADMINISTRATION
(PERGAMON-ELSEVIER SCIENCE LTD, 1995)
Cholestasis is associated with a marked increase in the release of canalicular membrane enzymes into bile. This phenomenon has been related to an increased lability of these canalicular membrane integral proteins to the ...
POSTCHOLESTATIC ALKALINE-PHOSPHATASE ACTIVITY AFTER RELIEF OF BILE-DUCT OBSTRUCTION IN THE RAT
(W B SAUNDERS CO, 1993)
The effects of obstructive cholestasis on the activity of alkaline phosphatase have been extensively studied in serum and liver tissue. However, very little is known about the activity of this enzyme in the postcholestatic ...