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Cardioprotection of benzolamide in a regional ischemia model: Role of ENOS/NO
(Academic Press Inc Elsevier Science, 2018-10)
Background: Recent studies from our laboratory show the cardioprotective action of benzolamide (BZ, carbonic anhydrase inhibitor) against ischemia-reperfusion injury. However, the mechanisms involved have not been fully ...
Carbonic anhydrase XIV in the normal and hypertrophic myocardium
(Academic Press Ltd - Elsevier Science Ltd, 2011-12)
Two AE3 transcripts, full-length (AE3fl) and cardiac (AE3c) are expressed in the heart. AE3 catalyzes electroneutral Cl−/HCO3− exchange across cardiomyocyte sarcolemma. AE proteins associate with carbonic anhydrases (CA), ...
Carbonic anhydrase inhibitors reduce cardiac dysfunction after sustained coronary artery ligation in rats
(Elsevier Science Inc, 2016-11)
Background Two potent carbonic anhydrase (CA) inhibitors with widely differing membrane permeability, poorly diffusible benzolamide (BZ), and highly diffusible ethoxzolamide (ETZ) were assessed to determine whether they ...
Contribución del co-transportador Na+- HCO3- y de la anhidrasa carbónica a las alteraciones por isquemia y reperfusión: rol de la mitocondria
(2019-03-01)
Los cardiomiocitos poseen en la membrana diferentes transportadores iónicos encargados de regular el pH intracelular (pHi). Cuando el pHi es ácido existen dos mecanismos alcalinizantes responsables de dicha regulación: el ...