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Superantígenos y su rol en enfermedades infecciosas
(Sociedad Médica de Santiago, 1998)
Superantigens increase the survival of mice bearing T cell lymphomas by inducing apoptosis of neoplastic cells
(Public Library of Science, 2010-11)
Superantigens bind to major histocompatibility complex class II molecules and interact with T cells expressing a particular T cell receptor Vβ inducing a strong proliferation/deletion response of the superantigen-reactive ...
Staphylococcus aureus: Superantigens and Autoimmunity
(2021-04-08)
Staphylococcus aureus is one of the most prevalent pathogens in the human population. S. aureus exhibits several escape mechanisms that allow it to evade host defenses. The main evasion mechanisms include inhibition of ...
egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation
(Frontiers Media S.A., 2019-12)
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, ...
egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation
(Frontiers Media, 2020-01)
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, ...
T-CELL-DEPENDENT ANTIBODY-RESPONSE TO STAPHYLOCOCCAL-ENTEROTOXIN-B
(Blackwell Science LtdOxfordInglaterra, 1995)
Functional Analysis of the TCR Binding Domain of Toxic Shock Syndrome Toxin-1 Predicts Further Diversity in MHC Class II/Superantigen/TCR Ternary Complexes
(American Association of Immunologists, 2003-07)
Superantigens (SAGs) aberrantly alter immune system function through simultaneous interaction with lateral surfaces of MHC class II molecules on APCs and with particular variable regions of the TCR beta-chain (Vbeta). To ...
Uptake and Intracellular Trafficking of Superantigens in Dendritic Cells
(Public Library Of Science, 2013-06)
Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to current paradigm, SAgs interact directly and ...
Airway exposure to staphylococcal enterotoxin A potentiates allergen-induced bone marrow eosinophilia and trafficking to peripheral blood and airways
(Amer Physiological SocBethesdaEUA, 2013)
Heterologous Chimeric Construct Comprising a Modified Bacterial Superantigen and a Cruzipain Domain Confers Protection Against Trypanosoma cruzi Infection
(Frontiers Media, 2020-06)
Chagas disease is an endemic chronic parasitosis in Latin America affecting more than 7 million people. Around 100 million people are currently at risk of acquiring the infection; however, no effective vaccine has been ...