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Protection from arthritis and myositis in a mouse model of acute chikungunya virus disease by bindarit, an inhibitor of monocyte chemotactic protein-1 synthesis

Rulli, Néstor E.; Rolph, Michael S.; Srikiatkhachorn, Anon; Anantapreecha, Surapee; Guglielmotti, Angelo; Mahalingam, Suresh (2011)

CCL2 mediates the circadian response to low dose endotoxin

Duhart, José Manuel; Brocardo, Lucila; Mul Fedele, Malena Lis; Guglielmotti, Angelo; Golombek, Diego Andrés (Elsevier, 2016-05)

The mammalian circadian system is mainly originated in a master oscillator located in the suprachiasmatic nuclei (SCN) in the hypothalamus. Previous reports from our and other groups have shown that the SCN are sensitive ...

Papel de CCL2 na adiposidade e intolerância à glicose induzidos em camundongos por dieta normocalórica/rica em carboidratos refinados

Renata Lacerda de Lima (Universidade Federal de Minas GeraisUFMG, 2011-10-11)

Obesity is associated with chronic inflammation and represents the risk factor for diabetes and metabolic syndrome. The results of works about the role of CC chemokine ligand 2 (CCL2) in adiposity and metabolic diseases ...

Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft

Gazzaniga, Silvina Noemí; Bravo, Alicia I.; Guglielmotti, Angelo; Rooijen, Nico van; Maschi, Fabricio; Vecchi, Annunciata; Mantovani, Alberto; Mordoh, Jose; Wainstok, Rosa (Elsevier, 2007)

Chemokines such as monocyte chemoattractant protein (MCP)-1 are key agonists that attract macrophages to tumors. In melanoma, it has been previously shown that variable levels of MCP-1/CCL2 appear to correlate with ...

Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

Gazzaniga, Silvina; Bravo, Alicia I.; Guglielmotti, Angelo; Van Rooijen, Nico; Maschi, Fabricio Alejandro; Vecchi, Annunciata; Mantovani, Alberto; Mordoh, José; Wainstok, Rosa (2007)

Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils

Santos, Théo Araújo; Luz, Nívea Farias; Andrade, Bruno Bezerril; Costa, Jaqueline França; Afonso, Lilian; Clarêncio, Jorge; Miranda, José Carlos; Bozza, Patrícia Torres; Reis, George A. dos; Brodskyn, Claudia Ida; Barral-Netto, Manoel; Borges, Valéria de Matos; Barral, Aldina Maria Prado (2011)

Neutrophils are considered the host's first line of defense against infections and have been implicated in the immunopathogenesis of Leishmaniasis. Leishmania parasites are inoculated alongside vectors' saliva, which is a ...

Critical Role of Monocyte Recruitment in Optic Nerve Damage Induced by Experimental Optic Neuritis

Aranda, Marcos Luis; Guerrieri, Diego; Piñero, Gonzalo Miguel; González Fleitas, María Florencia; Altschuler, Florencia; Dieguez, Hernán; Keller Sarmiento, María Inés; Chianelli, Mónica Silvia; Sande Casal, Pablo Horacio; Dorfman, Damián; Rosenstein, Ruth Estela (Humana Press, 2019-05)

Neuroinflammatory diseases are characterized by blood-brain barrier disruption (BBB) and leukocyte infiltration. We investigated the involvement of monocyte recruitment in visual pathway damage provoked by primary optic ...

Saliva from Lutzomyia longipalpis Induces CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Expression and Macrophage Recruitment

Teixeira, Clarissa Romero; Teixeira, Maria Jania; Gomes, Regis Bernardo Brandim; Santos, Claire da Silva; Andrade, Bruno Bezerril; Raffaele-Netto, Imbroinise; Silva, João Santana da; Guglielmotti, Angelo; Miranda, José Carlos; Barral, Aldina Maria Prado; Brodskyn, Claudia Ida; Barral-Netto, Manoel; Teixeira, Clarissa Romero; Teixeira, Maria Jania; Gomes, Regis Bernardo Brandim; Santos, Claire da Silva; Andrade, Bruno Bezerril; Raffaele-Netto, Imbroinise; Silva, João Santana da; Guglielmotti, Angelo; Miranda, José Carlos; Barral, Aldina Maria Prado; Brodskyn, Claudia Ida; Barral-Netto, Manoel (2005)

Saliva of bloodfeeding arthropods has been incriminated in facilitating the establishment of parasite in their host. We report on the leukocyte chemoattractive effect of salivary gland homogenate (SGH) from Lutzomyia ...

Saliva from Lutzomyia longipalpis Induces CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Expression and Macrophage Recruitment1

Teixeira, Clarissa Romero; Teixeira, Maria Jânia; Gomes, Regis Bernardo Brandim; Santos, Claire da Silva; Andrade, Bruno de Bezerril; Raffaele Netto, Imbroinise; Silva, João Santana da; Guglielmotti, Angelo; Miranda, José Carlos; Barral, Aldina Maria Prado; Brodskyn, Claudia Ida; Barral Netto, Manoel (2011)

Avaliação da atividade inflamatória da saliva de L. longipalpis utilizando o modelo do bolsão inflamatório

Teixeira, Clarissa Romero (Centro de Pesquisas Gonçalo Moniz, 2019)