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Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity
(Frontiers Media S.A., 2019-01)
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has pleiotropic effects on neuronal morphology and synaptic plasticity that underlie hippocampal circuit development and cognition. Recent advances established ...
Bioinformatics Approach to BDNF and BDNF-Related Disorders
(Bentham Science Publ Ltd, 2011-06-01)
Context: Currently, the keyword 'BDNF' retrieves 7388 publications in Pubmed, which point to many directions.Objective: This paper aims to uncover patterns that are hidden under this huge mass of studies and then to review ...
Loss of TrkB signaling due to status epilepticus induces a proBDNF-dependent cell death
(Frontiers Research Foundation, 2019-01-08)
Neurotrophins (NTs) are secretory proteins that bind to target receptors and influence many cellular functions, such as cell survival and cell death in neurons. The mammalian NT brain-derived neurotrophic factor (matBDNF) ...
Ação do BDNF na via dopaminérgica mesolímbica e seu papel na aquisição da memória em modelos de animais sob estresse
(Universidade Federal de Minas GeraisUFMG, 2015-10-27)
Brain-derived neurotrophic factor (BDNF) plays a key role in neuronal plasticity and memory. It has been described that BDNF mediates important processes, such as learning and memory, which make it a potential mediator of ...
Requirement for BDNF in the Reconsolidation of Fear Extinction
(2015-04-22)
Therapies based on the impairment of reconsolidation or the enhancement of extinction offer the possibility of decreasing the persistent recollection of distressing memories. However, the direct interplay between reconsolidation ...
CLASSICAL AVERSIVE CONDITIONING INDUCES INCREASED EXPRESSION OF MATURE-BDNF IN THE HIPPOCAMPUS AND AMYGDALA OF PIGEONS
(Pergamon-elsevier Science LtdOxfordInglaterra, 2013)
Short-time high-intensity exercise increases peripheral BDNF in a physical fitness-dependent way in healthy men
(2019-01-01)
BDNF is associated with brain health and positively modulated by exercise; however, the influence of physical fitness status on BDNF is incipient. This study investigated the BDNF response after acute-exercise sessions ...
BDNF isoforms: a round trip ticket between neurogenesis and serotonin?
(Wiley, 2016-07)
The brain-derived neurotrophic factor, BDNF, was discovered more than 30 years ago and, like other members of the neurotrophin family, this neuropeptide is synthetized as a proneurotrophin, the pro-BDNF, which is further ...