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Primary immunodeficiencies unravel critical aspects of the pathophysiology of autoimmunity and of the genetics of autoimmune disease
(SPRINGER/PLENUM PUBLISHERS, 2008)
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operation of the human immune system. Accordingly, PIDs associated with autoimmune manifestations provide insights into the ...
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases. However, some studies have demonstrated the ...
The role of regulatory T Cells in autoimmune orchitis
(Wiley Blackwell Publishing, Inc, 2018-12)
Regulatory T cells (Tregs) mediate tolerance to self-antigens maintaining immune homeostasis. Defects in the number and function of Tregs lead to aberrant immune responses to autologous components, thereby causing autoimmune ...
Autoimmune hepatitis and dermatomyositis: a rare association
(MEDFARMA-EDICOES MEDICAS, LDAALGES, 2012)
The association between autoimmune hepatitis and idiopathic inflammatory myopathies has been rarely described in literature. To our knowledge, there are only five reports of autoimmune hepatitis, all coursing with polymyositis. ...
Analysis of thyroglobulin gene polymorphisms in patients with autoimmune thyroiditis
(Springer, 2010-06)
The autoimmune thyroid disease is a complex disorder caused by a combination of genetic susceptibility and environmental factors, which are believed to initiate the autoimmune response to thyroid antigens. Identification ...
Adoptive transfer of autoimmune splenic dendritic cells to lupus-prone mice triggers a B lymphocyte humoral response
(Springer, 2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by increased autoantibody production that leads to multiple tissue injuries. Dendritic cells (DCs) are important orchestrators of immune responses ...
Autoimmune Hepatitis and Autoimmune Hepatitis Overlap With Sclerosing Cholangitis: Immunophenotype Markers in Children and Adolescents
(Lippincott, Williams & Wilkins, 2018)
Untangling galectin-driven regulatory circuits in autoimmune inflammation
(Elsevier, 2018-04)
Although significant progress has been made in understanding the mechanisms implicated in the pathogenesis and resolution of autoimmune inflammation, studies aimed at identifying mediators of these pathways are necessary ...
Autoimmune hepatitis-like disease in C57BL/6 mice infected with mouse hepatitis virus A59
(Elsevier Science, 2011)