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The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an ...
The 5q-syndrome and autoimmune phenomena: Report of three cases
(Elsevier B.V., 2006-04-01)
Myelodysplastic syndrome is a clonal hematopoietic stem cell disorder characterized by ineffective hematopoiesis, peripheral cytopenias and an additional risk to evolve to acute leukemia in up to 30% of the cases. Autoimmune ...
Primary immunodeficiencies unravel critical aspects of the pathophysiology of autoimmunity and of the genetics of autoimmune disease
(SPRINGER/PLENUM PUBLISHERS, 2008)
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operation of the human immune system. Accordingly, PIDs associated with autoimmune manifestations provide insights into the ...
Disorders of apoptosis: Mechanisms for autoimmunity in primary immunodeficiency diseases
(SPRINGER/PLENUM PUBLISHERS, 2008)
A number of primary immunodeficiency diseases represent a paradox of immunodeficiency and autoimmunity. In this minireview, we present basic concepts of apoptosis and disorder of apoptosis as one of the mechanisms to explain ...
Autoimmune Orchitis and Autoimmune Oophoritis
(Elsevier Academic Press Inc, 2013)
The etiology of gonadal failure with infertility in men and women may have a genetic, environmental, or autoimmune basis. The major support for an autoimmune basis has come from studies on patients with the autoimmune ...
Autoimmune disease aggregation in families with primary Sjögren's syndrome
Objective. Diverse autoimmune diseases may coexist in the same individual and in families, implying a common etiology. We examined the aggregation of autoimmune diseases among first-degree relatives (FDR) of patients with ...
Autoimmune polyglandular syndrome. Clinical experience in 21 cases
(1990)
The autoimmune polyglandular syndrome is characterized by the association of 2 or more endocrine disorders of autoimmune origin which may coexist with autoimmune disorders in other organs. Roughly 25% of patients with an ...
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases. However, some studies have demonstrated the ...
Autoimmune disease and multiple autoantibodies in 42 patients with RASopathies
(WILEY-BLACKWELLMALDEN, 2012)
The association of RASopathies [Noonan syndrome (NS) and Noonan-related syndromes] and autoimmune disorders has been reported sporadically. However, a concomitant evaluation of autoimmune diseases and an assessment of ...