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A liver metalloendopeptidase which degrades the circulating hypotensive peptide hormones bradykinin and atrial natriuretic peptide
(Associação Brasileira de Divulgação Científica, 1999-01-01)
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200. The purified enzyme ...
Oxytocin mediates atrial natriuretic peptide release and natriuresis after volume expansion in the rat
(Proc. Natl. Acad. Sci. USA, 1995)
Oxytocin mediates atrial natriuretic peptide release and natriuresis after volume expansion in the rat
(Proc. Natl. Acad. Sci. USA, 1995)
Our previous studies have shown that stimulation
of the anterior ventral third ventricular region increases
atrial natriuretic peptide (ANP) release, whereas
lesions of this structure, the median eminence, or removal of
the ...
GABA in the central amygdaloid nucleus modulates the electrolyte excretion and hormonal responses to blood volume expansion in rats
(Associação Brasileira de Divulgação Científica, 2009)
We investigated the involvement of GABAergic mechanisms of the central amygdaloid nucleus (CeA) in unanesthetized rats subjected to acute isotonic or hypertonic blood volume expansion (BVE). Male Wistar rats bearing cannulas ...
Oestradiol Potentiates Hormone Secretion and Neuronal Activation in Response to Hypertonic Extracellular Volume Expansion in Ovariectomised Rats
(WILEY-BLACKWELL, 2011)
Secretion of vasopressin (VP), oxytocin (OT) and atrial natriuretic peptide (ANP) is an essential mechanism for the maintenance of hydromineral homeostasis. Secretion of these hormones is modulated by several circulating ...
Cannabinoid CB1 receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes
(WILEY-BLACKWELLMALDEN, 2012)
1. The present study provides the first in vivo evidence that the cannabinoid CB1 receptor mediates the effects of dexamethasone on hormone release induced by changes in circulating volume and osmolality. Male adult rats ...
Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection
(Associação Brasileira de Divulgação Científica, 2000-10)
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas ...
Serotonergic mechanisms of the lateral parabrachial nucleus in renal and hormonal responses to isotonic blood volume expansion
(Amer Physiological Soc, 2007-03-01)
This study investigated the involvement of serotonergic mechanisms of the lateral parabrachial nucleus (LPBN) in the control of sodium (Na+) excretion, potassium (K+) excretion, and urinary volume in unanesthetized rats ...
Serotonergic mechanisms of the lateral parabrachial nucleus in renal and hormonal responses to isotonic blood volume expansion
(Amer Physiological Soc, 2007-03-01)
This study investigated the involvement of serotonergic mechanisms of the lateral parabrachial nucleus (LPBN) in the control of sodium (Na+) excretion, potassium (K+) excretion, and urinary volume in unanesthetized rats ...
Activation of lateral parabrachial afferent pathways and endocrine responses during sodium appetite regulation
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
Modulation of salt appetite involves interactions between the circumventricular organs (CVOs) receptive areas and inhibitory hindbrain serotonergic circuits. Recent studies provide support to the idea that the serotonin ...