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Hidrólise de atp e adp em líquor humano
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2008-03-27)
Adenine nucleotides hydrolysis is an important step of the neuromodulation of CNS and some of its breakdown products are able to protect the nervous tissue against brain injuries. The activity of NTPDase (EC 3.6.1.5, ...
Extracellular ATP hydrolysis in Caco-2 human intestinal cell line
(Elsevier Science, 2021-10)
Extracellular nucleotides and nucleosides activate signaling pathways that play major roles in the physiology and pathophysiology of the gastrointestinal tract. Ectonucleotidases hydrolyze extracellular nucleotides and ...
Kinetics of extracellular ATP in mastoparan 7-activated human erythrocytes
(Elsevier, 2013-10)
Background: The peptide mastoparan 7 (MST7) stimulated ATP release in human erythrocytes. We explored intraand extracellular processes governing the time-dependent accumulation of extracellular ATP (i.e., ATPe kinetics). ...
Development of a novel catalytic amyloid displaying a metal-dependent ATPase-like activity
(Elsevier B.V., 2017)
Amyloids are protein aggregates of highly regular structure that are involved in diverse pathologies such as Alzheimer's and Parkinson's disease. Recent evidence has shown that under certain conditions, small peptides can ...
Atividade da enzima NTPDase1 em linfócitos de pacientes em tratamento para leucemia linfoblástica aguda (LLA): alteração na hidrólise do ATP e ADP extracelulares.
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2006-08-25)
The NTPDase1 (E.C. 3.6.1.5, apyrase, CD39, ecto-ATP-diphosphohydrolase) enzymatic activity, which is responsible for hydrolyzing ATP and ADP nucleotides, was verified in lymphocytes from 56 patients under treatment for ...
The plasma membrane Ca2+ pump catalyzes the hydrolysis of ATP at low rate in the absence of Ca2+
(Elsevier Science Inc., 2010-03)
The plasma membrane Ca2+ ATPase catalyzed the hydrolysis of ATP in the presence of millimolar concentrations of EGTA and no added Ca2+ at a rate near 1.5% of that attained at saturating concentrations of Ca2+. Like the ...
Characterization of nucleotide-induced changes on the quaternary structure of human 70 kDa heat shock protein Hsp70.1 by analytical ultracentrifugation
(Korean Society Biochemistry & Molecular BiologySeoulCoreia do Sul, 2009)
ATP-binding cassette exporters: Structure and mechanism with a focus on P-glycoprotein and MRP1
(Bentham Science Publishers, 2019-09)
Background: Proteins that belong to the ATP-binding cassette superfamily include transporters that mediate the efflux of substrates from cells. Among these exporters, P-glycoprotein and MRP1 are involved in cancer multidrug ...