Buscar
Mostrando ítems 1-10 de 62
Stage-dependent C-reflex, pain-like behavior and opioid analgesia during the induction of chronic arthritis in rats
(Blackwell Publishing Ltd, 2014)
© 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.Chronic arthritis (CA) is a common clinical entity associated with persistent pain and limited response to opioid analgesic therapy. However, ...
Antinociceptive Effect of Rat D-Serine Racemase Inhibitors, L-Serine-O-Sulfate, and L-Erythro-3-Hydroxyaspartate in an Arthritic Pain Model
(The Scientific World Journal, 2012)
N-methyl-D-aspartic acid receptor (NMDAr) activation requires the presence ofD-serine, synthesized from L-serine by a pyridoxal
5 -phosphate-dependent serine racemase (SR). D-serine levels can be lowered by inhibiting the ...