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Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis
(2016-07-08)
The arginine repressor (ArgR) regulates arginine biosynthesis in a number of microorganisms and consists of two domains interlinked by a short peptide; the N-terminal domain is involved in DNA binding and the C-terminal ...
A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor
(2020-07-01)
The arginine repressor (ArgR) regulates the expression of genes involved in arginine biosynthesis. Upon attaining a threshold concentration of arginine in the cytoplasm, the trimeric C-terminal domain of ArgR binds three ...
Estudo da interação da proteína repressora de arginina (ArgR) de Clostridium botulinum, Porphyromonas gingivalis, Nocardia farcinica e Corynebacterium pseudotuberculosis com possíveis ligantes
(Universidade Estadual Paulista (Unesp), 2021-07-08)
Clostridium botulinum é o agente etiológico do botulismo, que ocorre principalmente após o consumo de alimentos contaminados com a toxina botulínica. Essa toxina impede a contração muscular e provoca paralisia, podendo ...
Operator recognition by the ROK transcription factor family members, NagC and Mlc
(Oxford Academic, 2015)
Determinación in vitro de la participación de la proteína hipotética SAUSA300_0063 en la activación del operón arc presente en el elemento móvil para el catabolismo de la arginina (ACME) en el clon pandémico USA300
(Maestría en Ciencias Básicas BiomédicasUniversidad El BosqueFacultad de Medicina, 2021)
En las últimas dos décadas se ha reportado la emergencia y rápida diseminación del Staphylococcus aureus resistente a meticilina clon USA300 con una amplia distribución y patogenicidad, causando al ser humano infecciones ...
Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats
(ELSEVIER SCIENCE INC, 2009)
Endothelial dysfunction has been linked to a decrease in nitric oxide (NO) bioavailability and attenuated endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation. The small (SK(Ca)) and intermediate (IK(Ca)) ...
Inibição do cross-talk entre alfa (v) beta (3) e VEGFR2 na angiogênese pela desintegrina DisBa-01
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2018-05-23)
Angiogenesis, a process by which new capillaries are formed from pre-existing vasculature, is essential in both physiological and pathological conditions. Inadequate balance between pro and antiangiogenic factors can ...
The Arabidopsis class I TCP transcription factor AtTCP11 is a developmental regulator with distinct DNA-binding properties due to the presence of a threonine residue at position 15 of the TCP domain
(Portland Press, 2011-04)
The TCP domain is a DNA-binding domain present in plant transcription factors that modulate different processes. In the present study, we show that Arabidopsis class I TCP proteins are able to interact with a dyad-symmetric ...