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Relative CO(2)/NH(3) selectivities of mammalian aquaporins 0-9
(American Physiological SocietyBethesda, 2013-05-15)
Previous work showed that aquaporin 1 (AQP1), AQP4-M23, and AQP5 each has a characteristic CO(2)/NH(3) and CO(2)/H(2)O permeability ratio. The goal of the present study is to characterize AQPs 0-9, which traffic to the ...
Maternal protein restriction differentially alters the expression of AQP1, AQP9 and VEGFr-2 in the epididymis of rat offspring
(2019-02-01)
Background: Maternal protein restriction causes sperm alterations in the offspring, most of which are associated with epididymal functions. Because fluid reabsorption/secretion dynamics in the epididymal environment play ...
Maternal Protein Restriction Modulates Angiogenesis and AQP9 Expression Leading to a Delay in Postnatal Epididymal Development in Rat
(2019-09-17)
The maternal nutritional status is essential to the health and well-being of the fetus. Maternal protein restriction during the perinatal stage causes sperm alterations in the offspring that are associated with epididymal ...
The blocking of aquaporin-3 (AQP3) impairs extravillous trophoblast cell migration
(Academic Press Inc Elsevier Science, 2018-05)
Several aquaporins (AQPs) are expressed in extravillous (EVT) and villous trophoblast cells. Among them, AQP3 is the most abundant AQP expressed in chorionic villi samples from first trimester, followed by AQP1 and AQP9. ...
Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel
(AMER PHYSIOLOGICAL SOC, 2010)
Chen LM, Zhao J, Musa-Aziz R, Pelletier MF, Drummond IA, Boron WF. Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel. Am J Physiol Regul Integr Comp Physiol 299: ...
Evidence for insulin-mediated control of AQP9 expression in human placenta
(Elsevier, 2011-12)
The AQP9 gene contains a negative insulin response element, suggesting that it may be modulated by insulin. Previously, we reported AQP9 overexpression in preeclamptic placentas but a lack of functionality of AQP9 in water ...
A highly specific and sensitive nanoimmunosensor for the diagnosis of neuromyelitis optica spectrum disorders
(Nature Publishing Group, 2019-11-06)
A precise diagnosis for neuromyelitis optica spectrum disorders (NMOSD) is crucial to improve patients' prognostic, which requires highly specific and sensitive tests. The cell-based assay with a sensitivity of 76% and ...
AQP2-induced acceleration of renal cell proliferation involves the activation of a regulatory volume increase mechanism dependent on NHE2
(Wiley-liss, Div John Wiley & Sons Inc, 2016-05)
We have previously shown in renal cells that expression of the water channel Aquaporin 2 (AQP2) increases the rate of cell proliferation by shortening the transit time through the S and G2/M phases of the cell cycle. This ...
AQP2 can modulate the pattern of Ca 2+ transients induced by store-operated Ca 2+ entry under TRPV4 activation
(Wiley-liss, Div John Wiley & Sons Inc, 2017-12)
There is increasing evidence indicating that aquaporins (AQPs) exert an influence in cell signaling by the interplay with the TRPV4 Ca2+ channel. Ca2+ release from intracellular stores and plasma membrane hyperpolarization ...
Expression of aquaporin-3 (AQP3) in placentas from pregnancies complicated by preeclampsia
(Elsevier, 2017-11)
Recently, we have reported that the blocking of AQP3 abrogates the apoptotic response of the trophoblast. Since trophoblast apoptosis is exacerbated in preeclampsia, we hypothesized that placental AQP3 is increased in these ...